Volume : 09, Issue : 06, June – 2022
Title:
50.FORMULATION AND EVALUATION OF MATRIX TYPE TRANSDERMAL PATCHES OF BENAZEPRIL HYDROCHLORIDE
Authors :
Tanvir Y. Shaikh*, Himali R. Patil*, Dr. Bharat V. Jain, Dr. Sandip R. Pawar
Abstract :
In the present study an attempt has been made to formulate and evaluate the transdermal patches of benazepril hydrochloride using various types of polymers (Eudragit L100, Eudragit S100 and ethylcellulose).
The results of compatibility studies by Fourier transform infrared spectroscopy and differential scanning Calorimetry which shows no interaction between the drug and polymers.
The polymers Eudragit L100 and Eudragit S100 used for the formulation of transdermal patches exhibited milestone film forming property as compared to ethylcellulose.
The patches designed by using Eudragit L100 and Eudragit S100 were thin, flexible, smooth and transparent where as the patches prepared by using ethylcellulose were thin, flexible, smooth and opaque.
The weight variation test showed less variation in weight and suggesting uniform distribution of drug and polymer over the mercury surface.
Keywords: Transdermal patches, Benazepril hydrochloride, polymers Eudragit L100, Eudragit S100, drug and polymer.
Cite This Article:
Please cite this article in press Himali R. Patil et al, Formulation And Evaluation Of Matrix Type Transdermal Patches Of Benazepril Hydrochloride., Indo Am. J. P. Sci, 2022; 09(6).,
Number of Downloads : 10
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