Volume : 09, Issue : 03, March – 2022

Title:

23.PREVALENCE AND PREDICTORS OF GERD IN PREGNANT WOMEN AND ITS EFFECT ON QUALITY OF LIFE AND PREGNANCY OUTCOMES

Authors :

Dr Bushra Ahmad, Dr Ayman Tahir, Dr Muhammad Ali, Dr Momina Ahmad

Abstract :

Introduction: In accordance with the new Montreal criteria, Gastroesophageal Reflux Disease (GERD) is classified as a disease that is related to troublesome symptoms and/or complications because of reflux of stomach contents into the esophagus. Objectives: The main objective of the study is to find the prevalence and predictors of GERD in pregnant women and its effect on quality of life and pregnancy outcomes. Material and methods: This cross sectional study was conducted in Nishtar medical university during 2021. The GerdQ was used to diagnose GERD. The GerdQ comprises four predictors of GERD: (1) heartburn and regurgitation (symptoms of GERD, Montreal definition); (2) sleep disturbance; (3) use of medication (predictors of GERD, DIAMOND study), and (4) epigastric pain and nausea. (1) and (2) are positive predictors. (3) and (4) are negative predictors. Results: There were no significant differences between the GERD and non-GERD groups in terms of mean age, gravidity, education, and trimester. Of the 94 pregnant women, 28 were diagnosed with GERD. Conclusion: It is concluded that the prevalence of GERD in late pregnancy is high in Pakistan and is associated with poor QoL in pregnant women.

Cite This Article:

Please cite this article in press Bushra Ahmad et al, Prevalence And Predictors Of GERD In Pregnant Women And Its Effect On Quality Of Life And Pregnancy Outcomes., Indo Am. J. P. Sci, 2022; 09(3).

Number of Downloads : 10

References:

1. Fill Malfertheiner S, Malfertheiner MV, Monkemuller K, Röhl FW, Malfertheiner P, et al. (2009) Gastroesophageal reflux disease and management in advanced pregnancy: a prospective survey. Digestion 79: 115-120. Link: https://bit.ly/3dgVZml
2. Ramya RS, Jayanthi N, Alexander PC, Vijaya S, Jayanthi V (2014) Gastroesophageal reflux disease in pregnancy: a longitudinal study. Trop Gastroenterol 35: 168-172. Link: https://bit.ly/3w9KNk3
3. Rey E, Rodriguez-Artalejo F, Herraiz MA, Sanchez P, Alvarez-Sanchez A, et al. (2007) Gastroesophageal reflux symptoms during and after pregnancy: a longitudinal study. Am J Gastroentero 102: 2395-2400. Link: https://bit.ly/2QHRB8l
4. Fisher RS, Roberts GS, Grabowski CJ, Cohen S (1978) Altered lower esophageal sphincter function during early pregnancy. Gastroenterology 74: 1233-1237. Link: https://bit.ly/3u2Onux
5. Nagler R, Spiro HM (1961) Heartburn in late pregnancy. Manometric studies of esophageal motor function. J Clin Invest 40: 954-970. Link: https://bit.ly/39mS7PR
6. Jones R, Junghard O, Dent J, Vakil N, Halling K, et al. (2009) Development of the GerdQ, a tool for the diagnosis and management of gastro-oesophageal reflux disease in primary care. Aliment Pharmacol Ther 30: 1030-1038. Link: https://bit.ly/3rqJ5HG
7. Fill Malfertheiner S, Malfertheiner MV, Kropf S, Costa SD, Malfertheiner P (2012) A prospective longitudinal cohort study: evolution of GERD symptoms during the course of pregnancy. BMC Gastroenterol 12: 131. Link: https://bit.ly/2PiCeTF
8. Naumann CR, Zelig C, Napolitano PG, Ko CW (2012) Nausea, vomiting, and heartburn in pregnancy: a prospective look at risk, treatment, and outcome. J Matern Fetal Neonatal Med 25: 1488-1493. Link: https://bit.ly/31sI4nP
9. Gerson LB (2012) Treatment of gastroesophageal reflux disease during pregnancy. Gastroenterol Hepatol 8: 763-764. Link: https://bit.ly/3ss16Xn
10. Pasternak B, Hviid A (2010) Use of proton-pump inhibitors in early pregnancy and the risk of birth defects. New England Journal Medicine 363: 2114-2123. Link: https://bit.ly/39kvdII