Volume : 09, Issue : 05, May – 2022
Title:
44.AN REVIEW ARTICLE ON THE ANTI-ULCER ACTIVITY OF SOME MEDICINAL PLANTS
Authors :
Kavita Malviya*, Anant Kumar Patel, P.K. Dubey
Abstract :
Peptic ulcer is one of the most common gastrointestinal diseases. The exact causes of peptic ulcer disease are not known but it may be result from an imbalance between acid-pepsin secretion and mucosal defence factors. Peptic ulcer disease occurs mainly due to consumption of NSAIDs, infection by H. pylori, stress, or due to a pathological condition such as Zollinger –Ellison Syndrome. Nature provides a number of medicines and perhaps all solutions for human illnesses. So far, nature supplies many clinically useful drugs. Ulcer is a major increasing health problem. Nowadays, there are several synthetic medications available for the treatment of peptic ulcers, but these drugs are expensive and are likely to produce more side effects than herbal drugs. Certain antiulcer drugs such as proton pump inhibitors and H2 receptor antagonists are used to treat peptic ulcers. However, these drugs have shown disease relapse, side effects, and even drug interactions. Numerous medicinal plants have anti-ulcer activity and are useful in the treatment of peptic ulcers. The aim of this review is to find out more about the anti-ulcer properties of herbal medicines. The present article reviews the antiulcerogenic and ulcer healing property of Ocimum sanctum, Allophylus serratus, Desmodium gagenticum, Azadirachta indica, Hemidesmus racemosus, Asparagus racemosus, and Musa sapientum. We have brought to light some of the important plants reported for their anti-ulcer and ulcer healing properties. Ayurvedic knowledge supported by modern science is necessary to isolate, characterize and normalize the active components of herbal sources for antiulcerative activity.
KEYWORDS: Antiulcer activity, Ethanolic extract, Aspirin-induced ulcer model, NSAIDs.
Cite This Article:
Please cite this article in press Kavita Malviya et al, An Review Article On The Anti-Ulcer Activity Of Some Medicinal Plants., Indo Am. J. P. Sci, 2022; 09(5).,
Number of Downloads : 10
References:
1. P.C. Dandiya, S.K. Kulkarni. Introduction to Pharmacology. Vallabh Prakashan New Delhi, 2005. pp. 247.
2. Padmaja Uday Kumar. Textbook of medical Pharmacology, CBS publishers, New Delhi, 2005 pp. 317.
3. Mohammed A., Ravi Kumar J., Santosh H.Y., and Naga Shruthi M.H. Antiulcer activity of acidophilus carnosus leaf extracts in pylorus ligation rats. Indian Drugs 45 (12): 979. (2008).
4. Iyer D. and Uma D.P. Effect of Murraya Koenigii (L) on radiation induced rate of lipid peroxidation in Swiss albino mice. Indian Drugs 46 (2): 160 (2009).
5. S.K. Bhattacharjee. Handbook of Medicinal Plant. Pointer publishers, Jaipur, 2001, pp.230.
6. 6.M.S. Pande, S.P.B. N Gupta, A. Pathak. Hepatoprotective Activity of Murraya Koenigii Linn Bark. Journal of Herbal Medicine and Toxicology 3(1): 69-71 (2009).
7. Tachibana, Y., Kikuzaki, H., Laic, N.H. and Nakatani, N. Journal of Agriculture and Food Chemistry 49(11): 5589 (2001).
8. Achyut Narayan Kesari, Rajesh Kumar Gupta and Geeta Watal. Hypoglycemic effect of Murraya Koenigii on normal and all oxandiabeticrabbits. Journal of Ethnopharmacology 97(2): 247-251 (2005).
9. S.M. Zachariah, P. Muthumani, K. Ramaseshu. Photochemistry and Antimicrobial screening of stem bark of murraya koenigii (Linn)spreng. The Internet Journal of Pharmacology 6(2): (2009).
10. Adebajo, A.C., Ayoola, O.F., Iwalewa, E.O., Akindahunsi, A.A., Omisore, N.O.,Adewunmi, C.o. and Adenowo, T.K.phytomedicine13 (4):246 (2006).
11. John wilking Einstein, Johnson. K. Mathias, Kuntal Das, I.S.R. Nidhaya and G. Sudhakar. Comparative Hepatoprotective Activity of Leaf Extracts of Murraya Koenigii from Indian Subtropics. Indian Journal of Natural Product23(1): 13-17(2007).
12. Brodie DA, Hooke KF. The effect of vasoactive agents on stress-induced gastric hemorrhage in the rat. Digestion1971; 4:193-204.
13. Chul-Hong P, Hyung-US, Minsik S, Sang-Han L. Protective effect of Acer mono Max. sap on water immersion restraint stress-induced gastric ulceration. Exp Ther Med 2011; 2(5):843-848.
14. Estakhr J, Sanchooli N, NajafiSh, Javdan N. Anti-inflammatory activity of ethanolic extract of Physalisal kekengi. Res J Pharm Biol Chem Sci 2011;2(3):421-425.
15. Schmeda-Hirschmann G, Yesilada E. Traditional medicine and gastroprotective crude drugs. Ethnopharmacology 2005; 100:61-66.
16. Tripathi KD. Gastrointestinal Drugs. Essentials of medical pharmacology Edn 6, Jaypee India, 2009, 627-638.
17. Jamal A, Siddiqui A, Tajuddin, Jafri MA. A review on gastric Ulcer remedies used in Unani system of medicine. Natural product radiance2006; 5(3):153-159.
18. Paris HS, Daunay MC, Janick J, Occidental diffusion of cucumber (Cucumis sativus) 500–1300 CE: two routes to Europe. Annals of Botany 2011;1-10.
19. Yeboah MA, Xuehao C, Feng CR, Liang G, Gu M, A genetic linkage map of cucumber (Cucumis sativus L) combining SRAP and ISSR markers. African Journal of Biotechnology 2007; 6(24):2784-2791.