Volume : 09, Issue : 05, May – 2022

Title:

67.REVIEW- ROLES OF PHARMACIST IN EMERGENCY CASES OF TOXICOLOGY
‬

Authors :

Eman awadullah Alharbi, Ali haseen alzahrani, Abdullah Muhsen Nasser Ezzi, Abdu Hassan Yahya Kahlani, Ahmed Salem Alkhayat, Bandar Mazyad Safar Alharthi, Ahmed Muhji Safar Almuqati, Bedour Bakur Mohammed Barasyn

Abstract :

In many industrialized countries, pharmacists’ roles have changed from the conventional practice of dispensing drugs to directly or indirectly contributing to improved patient health outcomes. They provide hospital services and patient care, including emergency department (ED) services.
By assisting in the early diagnosis of toxic exposures and instructing emergency workers on the right storage, selection, and use of antidotal therapies, pharmacists can play a critical role in decreasing poisoning and overdose injuries and deaths. Patients are often new to emergency care personnel, may be unable to disclose critical medical information, and may require time-sensitive interventions.

Cite This Article:

Please cite this article in Eman awadullah Alharbi et al, Review- Roles Of Pharmacist In Emergency Cases Of Toxicology, Indo Am. J. P. Sci, 2022; 09 (05).

Number of Downloads : 10

References:

1. Leape LL, Cullen DJ, Clapp MD, et al. Pharmacist participation on physician rounds and adverse drug events in the intensive care unit. JAMA. 1999;282:267-270.
2. Morgan SR, Acquisto NM, Coralic Z, et al. Clinical pharmacy services in the emergency department. Am J Emerg Med. 2018;36:1727-1732.
3. Croskerry P, Sinclair D. Emergency medicine: a practice prone to error? CJEM. 2001;3:271-276.
4. Croskerry P, Shapiro M, Campbell S, et al. Profiles in patient safety: medication errors in the emergency department. Acad Emerg Med. 2004;11:289-299.
5. Roman C, Edwards G, Dooley M, Mitra B. Roles of the emergency medicine pharmacist: a systematic review. Am J Health Syst Pharm. 2018;75:796-806.
6. Pandey NR. Emergency medicine in Nepal: present practice and direction for future. Int J Emerg Med. 2016;9:20.
7. Bates, D.W.; Cullen, D.J.; Laird, N.; Petersen, L.A.; Small, S.D.; Servi, D.; Laffel, G.; Sweitzer, B.J.; Shea, B.F.; Hallisey, R.; et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. JAMA 1995, 274, 29–34.
8. Nebeker, J.R.; Barach, P.; Samore, M.H. Clarifying adverse drug events: A clinician’s guide to terminology, documentation, and reporting. Ann. Intern. Med. 2004, 140, 795–801.
9. Naranjo, C.A.; Busto, U.; Sellers, E.M.; Sandor, P.; Ruiz, I.; Roberts, E.A.; Janecek, E.; Domecq, C.; Greenblatt, D.J. A method for estimating the probability of adverse drug reactions. Clin. Pharmacol. Ther. 1981, 30, 239–245.
10. Khan, L.M. Comparative epidemiology of hospital-acquired adverse drug reactions in adults and children and their impact on cost and hospital stay—A systematic review. Eur. J. Clin. Pharmacol. 2013, 69, 1985–1996.
11. Hohl, C.M.; Nosyk, B.; Kuramoto, L.; Zed, P.J.; Brubacher, J.R.; Abu-Laban, R.B.; Sheps, S.B.; Sobolev, B. Outcomes of emergency department patients presenting with adverse drug events. Ann. Emerg. Med. 2011, 58, 270–279.e274.
12. Lahue, B.J.; Pyenson, B.; Iwasaki, K.; Blumen, H.E.; Forray, S.; Rothschild, J. National burden of preventable adverse drug events associated with inpatient injectable medications: Healthcare and medical professional liability costs. Am. Health Drug Benefits 2012, 5, 1–10.
13. Martins, A.C.; Giordani, F.; Rozenfeld, S. Adverse drug events among adult inpatients: A meta-analysis of observational studies. J. Clin. Pharm. Ther. 2014, 39, 609–620.
14. Tache, S.V.; Sonnichsen, A.; Ashcroft, D.M. Prevalence of adverse drug events in ambulatory care: A systematic review. Ann. Pharmacother. 2011, 45, 977–989.
15. Smith M, Bates DW, Bodenheimer T, Cleary PD. Why pharmacists belong in the medical home. Health Aff (Millwood). 2010;29:906-913.
16. Thomas MC, Acquisto NM, Shirk MB, Patanwala AE. A national survey of emergency pharmacy practice in the United States. Am J Health Syst Pharm. 2016;73:386–94.
17. Marraffa JM, Cohen V, Howland MA. Antidotes for toxicological emergencies:A practical review. Am J Health Syst Pharm. 2012;69:199–212.
18. Ortmann MJ, Johnson EG, Jarrell DH, Bilhimer M, Hayes BD, Mishler A, et al. ASHP guidelines on emergency medicine pharmacist services. Am J Health Syst Pharm. 2021;78:261–75.
19. Farmer BM, Hayes BD, Rao R, Farrell N, Nelson L. The role of clinical pharmacists in the emergency department. J Med Toxicol. 2018;14:114–6.
20. Vassilev ZP, Marcus SM. The impact of a poison control center on the length of hospital stay for patients with poisoning. J Toxicol Environ Health A. 2007;70:107–10.
21. Bunn TL, Slavova S, Spiller HA, Colvin J, Bathke A, Nicholson VJ. The effect of poison control center consultation on accidental poisoning inpatient hospitalizations with preexisting medical conditions. J Toxicol Environ Health A. 2008;71:283–8.
22. Friedman LS, Krajewski A, Vannoy E, Allegretti A, Wahl M. The association between U. S. Poison Center assistance and length of stay and hospital charges. Clin Toxicol (Phila) 2014;52:198–206.
23. Thomas MC, Acquisto NM, Shirk MB, Patanwala AEA. National survey of emergency pharmacy practice in the United States. Am J Health Syst Pharm. 2016;73:386–394.
24. Mazer-Amirshahi M, Hawley KL, Zocchi M, et al. Drug shortages: implications for medical toxicology. Clin Toxicol. 2015;53(6):519–524.
25. Rosoff PM, Patel KR, Scates A, Rhea G, Bush PW, Govert JA. Coping with critical drug shortages. Arch Intern Med. 2012;172(19):1494–1496.
26. Patanwala AE, Hays DP, Sanders AB, et al. Severity and probability of harm of medication errors intercepted by an emergency department pharmacist. Int J Pharm Pract. 2011;19:358–362.
27. Patanwala AE, Sanders AB, Thomas MC, et al. A prospective, multicenter study of pharmacist activities resulting in medication error interception in the emergency department. Ann Emerg Med. 2012;59:369–373.
28. Wynn PM, Zou K, Young B, et al. Prevention of childhood poisoning in the home: overview of systematic reviews and a systematic review of primary studies. Int J Inj Contr Saf Promot. 2016;23(1):3-28.
29. Spiller HA, Ackerman JP, Spiller NE, Casavant MJ. Sex- and age-specific increases in suicide attempts by self-poisoning in the United States among youth and young adults from 2000 to 2018. J Pediatr. 2019;210:201-208.
30. Bond GR, Woodward RW, Ho M. The growing impact of pediatric pharmaceutical poisoning. J Pediatr. 2012;160(2):265-270.e1.
31. Yip L, Bixler D, Brooks DE, et al. Serious adverse health events, including death, associated with ingesting alcohol-based hand sanitizers containing methanol—Arizona and New Mexico, May-June 2020. MMWR Morb Mortal Wkly Rep. 2020;69(32):1070-1073.
32. Kerns W II. Management of betaadrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am. 2007; 25:309-31.
33. DeWitt CR, Waksman JC. Pharmacology, pathophysiology and management of calcium channel blocker and beta-blocker toxicity. Toxicol Rev. 2004; 23:223-38.
34. Marraffa JM, Holland MG, Stork CM et al. Diethylene glycol: widely used solvent presents serious poisoning potential. J Emerg Med. 2007; 35:401-6.
35. Hasbani MJ, Sansing LH, Perrone J et al. Encephalopathy and peripheral neuropathy following diethylene glycol ingestion. Neurology. 2005; 64:1273-5.
36. Hari P, Jain Y, Kabra SK. Fatal encephalopathy and renal failure caused by diethylene glycol poisoning. J Trop Pediatr.2006; 52:442-4.