Please cite this article in press Bhagyashri Patel et al, Review Nutraceuticals New Era Of Pharmacy.,Indo Am. J. P. Sci, 2022; 09(11).

1. Kalra EK. Nutraceutical – Definition and introduction. AAPS Pharm Sci 2003;5: E25.
2. Zhao J. Nutraceuticals, Nutritional Therapy, Phytonutrients, and Phototherapy for Improvement of Human Health: A Perspective on Plant Biotechnology Application, Bentham Science Publishers; 2007. Available from: http://www.benthamscience.com/
Biot/samples/biot1‑1/Zhao.pdf. [Last accessed on 2012 Mar 24].
3. . Chauhan B, Kumar G, Kalam N, Ansari SH. Current Concepts and prospects of herbal nutraceutical: A review. J Adv Pharm Technol Res 2013;4:4‑8.
4. Zeisel SH. Regulation of “nutraceuticals”. Science 1999;285:1853‑5.
5. Hardy G. Nutraceuticals and functional foods: Introduction and meaning. Nutrition 2000;16:688‑9.
6. BaradaranA, MadihiY, MerrikhiA, Rafieian‑Kopaei M, Nasri H. Serum lipoprotein (a) in diabetic patients with various renal function not yet on dialysis. Pak J Med Sci 2013;29 Suppl: 354‑7.
7. Nasri H. Impact of diabetes mellitus on parathyroid hormone in hemodialysis patients. J Parathyr Dis 2013;1:9‑11.
8. MadihiY, MerrikhiA, BaradaranA, Rafieian‑kopaei M, Shahinfard N, Ansari R, et al. Impact of sumac on postprandial high‑fat oxidative stress. Pak J Med Sci 2013;29:340‑5.
9. Setorki M, Rafieian‑Kopaei M, MerikhiA, Heidarian E, Shahinfard N, Ansari R, et al. Suppressive impact of anethum graveolens consumption on biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits. Int J Prev Med 2013;4:889‑95.
10. Khosravi‑Boroujeni H, Mohammadifard N, Sarrafzadegan N, Sajjadi F, Maghroun M, Khosravi A, et al. Potato consumption and cardiovascular disease risk factors among Iranian population. Int J Food Sci Nutr 2012;63:913‑20.
11. Khosravi‑Boroujeni H, Sarrafzadegan N, Mohammadifard N, Sajjadi F, Maghroun M, Asgari S, et al. White rice consumption and CVD risk factors among Iranian population. J Health Popul Nutr 2013;31:252‑61.
12. Shirzad H, Burton RC, Smart YC, Rafieian‑kopaei M, Shirzad M. Natural cytotoxicity of NC‑2+cells against the growth and metastasis of WEHI‑164 fibrosarcoma. Scand J Immunol 2011;73:85‑90.13.
13. ShirzadM, KordyazdiR, ShahinfardN, NikokarM. Does Royal Jelly affect tumor cells? J HerbMed Pharmacol 2013;2:45‑8. Rafieian‑Kopaie M, Baradaran A. Plants antioxidants: From laboratory to clinic. J Nephropathol 2013;2:152‑3.
14. Akhlaghi M, Shabanian G, Rafieian‑Kopaei M, Parvin N, Saadat M, Akhlaghi M. Citrus aurantium blossom and preoperative anxiety. Rev Bras Anestesiol 2011;61:702‑12.
15. Roohafza H, Sarrafzadegan N, Sadeghi M,Rafieian‑Kopaei M, Sajjadi F, Khosravi‑Boroujeni H. The association between stress levels and food Consumption among Iranian population. Arch Iran Med 2013;16:145‑8.
16. Baradaran A, Nasri H, Nematbakhsh M, Rafieian‑Kopaei M. Antioxidant activity and preventive Effect of aqueous leaf extract of Aloe Vera on Gentamicin‑induced nephrotoxicity in male Wistar rats. Clin Ter 2014;165:7‑11.
17. Nasri H, Tavakoli M, Ahmadi A, Baradaran A, Nematbakhsh M, Rafieian‑Kopaei M. Ameliorative Effect of melatonin against contrast media induced renal Tubular cell injury. Pak J Med Sci 2014;30:261‑5.
18. Parsaei P, Karimi M, Asadi SY, Rafieian‑Kopaei M. Bioactive components and preventive effect of green Tea (Camellia sinensis) extract on post‑laparotomy Intra‑abdominal adhesion in rats. Int J Surg 2013;11:811‑5.
19. Kafash‑Farkhad N, Asadi‑Samani M , Rafieian‑Kopaei M. A review on phytochemistry and Pharmacological effects of Prangos ferulacea (L.) Lindl. Life Sci J 2013;10:360‑7.
20. Mirhoseini M, Baradaran A, Rafieian‑Kopaei M. Medicinal plants, diabetes mellitus and urgent needs. J HerbMed Pharmacol 2013;2:53‑4.
21. Akbari F, Ansari‑Samani R, Karimi A, Mortazaei S, Shahinfard N, Rafieian‑Kopaei M. Effect of turnip on Glucose and lipid profiles of alloxan‑induced diabetic Rats. Iran J Endocrinol Metab 2013;14:1‑7.
22. Bahmani M, Vakili‑Saatloo N, Maghsoudi R, Momtaz H, Saki K, Kazemi‑Ghoshchi B, et al. A comparative study on the effect of ethanol extract of Wild Scrophularia deserti and streptomycin on Brucellla Melitensis. J HerbMed Pharmacol 2013;2:17‑20.
23. Karimi A, Moradi MT, Saeedi M, Asgari S, Rafieian‑Kopaei M. Antiviral activity of Quercus Persica L.: High efficacy and low toxicity. Adv Biomed Res 2013;2:36.
24. Rafieian‑Kopaie M. Metformin and renal injury Protection. J Renal Inj Prev 2013;2:91‑2.
25. Rafieian‑Kopaei M, Baradaran A, Merrikhi A, Nematbakhsh M, Madihi Y, Nasri H. Efficacy of Co‑administration of garlic extract and metformin for Prevention of gentamicin‑renal toxicity in wistar rats: A Biochemical Study. Int J Prev Med 2013;4:258‑64.
26. Kiani MA, Khodadad A, Mohammadi S, Ghayour Mobarhan M, Saeidi M, Jafari SA, et al. Effect of Peppermint on pediatrics’ pain under endoscopic Examination of the large bowel. J HerbMed Pharmacol 2013;2:41‑4.
27. Hosseini‑asl K, Rafieian‑kopaei M. Can patients With active duodenal ulcer fast Ramadan? Am J Gastroenterol 2002;97:2471‑2
28. GrammatikosAP. The genetic and environmental basis Of atopic diseases. Ann Med 2008;40:482‑95.
29. Kruger CL, Murphy M, DeFreitas Z, Pfannkuch F, Heimbach J. An innovative approach to the determination Of safety for a dietary ingredient derived from a new Source: Case study using a crystalline lutein product. Food Chem Toxicol 2002;40:1535‑49.
30. Glenville M. Nutritional supplements in pregnancy: Commercial push or evidence based? Curr Opin Obstet Gynecol 2006;18:642‑7.
31. Brookmeyer R, Johnson E, Ziegler‑Graham K, Arrighi HM. Forecasting the global burden of Alzheimer ’s disease. Alzheimers Dement 2007;3:186‑91.
32. Rabiei Z, Rafieian‑Kopaei M, Heidarian E, Saghaei E, Mokhtari S. Effects of Zizyphus jujube extract on Memory and learning impairment induced by bilateral Electric lesions of the nucleus basalis of Meynert in rat. Neurochem Res 2014;39:353‑60.
33. Rabiei Z, Rafieian‑kopaei M, Heidarian E, Saghaei E, Mokhtari S. Effects of Zizyphus jujube extract on Memory and learning impairment induced by bilateral Electric lesions of the nucleus basalis of meynert in rat. Neurochem Res 2014;39:353-60.
34. Rabiei Z, Rafieian‑Kopaei M, Mokhtari S, Alibabaei Z, Shahrani M. The effect of pretreatment with different Doses of Lavandula officinalis ethanolic extract on Memory, learning and nociception. Biomed Aging Pathol 2013.
35. Ghorbani A, Rafieian‑Kopaei M, Nasri H.Lipoprotein (a): More than a bystander in the etiology of Hypertension? A study on essential hypertensive patients Not yet on treatment. J Nephropathol 2013;2:67‑70.
36. Behradmanesh S, Nasri P. Serum cholesterol and LDL‑C in association with level of diastolic blood Pressure in type 2 diabetic patients. J Renal Inj Prev 2012;1:23‑6
37. Nasri H. Comment on: Serum cholesterol and LDL‑C In association with level of diastolic blood pressure in Type 2 diabetic patients. J Renal Inj Prev 2012;1:13‑4.
38. Asgary S, Keshvari M, Sahebkar A, Hashemi M, Rafieian‑Kopaei M. Clinical investigation of the acute Effects of pomegranate juice on blood pressure and Endothelial function in hypertensive individuals. ARYA Atheroscler 2013;9:326‑31.
39. Nasri H, Sahinfard N, Rafieian M, Rafieian S, Shirzad M, Rafieian‑kopaei M. Effects of Allium Sativum on liver enzymes and atherosclerotic risk Factors. J HerbMed Pharmacol 2013;2:23‑8.
40. Rafieian‑Kopaei M. Medicinal plants and the human Needs. J HerbMed Plarmacol 2012;1:1‑2.
41. Hu FB, Willett WC. Optimal diets for prevention of coronary heart disease. JAMA 2002;288:2569‑78.
42. Behradmanesh S, Nasri H. Association of serum Calcium with level of blood pressure in type 2 diabetic Patients. J Nephropathol 2013;2:254‑7.
43. HajivandiA, Amiri M. World kidney day 2014: Kidney Disease and elderly. J Parathyr Dis 2014;2:3‑4.
44. Shahbazian H. World diabetes day; 2013. J Renal Inj Prev 2013;2:123‑4.
45. Asgary S, Sahebkar A, Afshani M, Keshvari M. Haghjooyjavanmard SH, Rafieian‑Kopaei M. Clinical evaluation of blood pressure lowering, Endothelial function improving, hypolipidemic and Anti‑inflammatory effects of pomegranate juice in Hypertensive subjects. Phytother Res 2013
46. Gharipour M, Ramezani MA, Sadeghi M, Khosravi A, Masjedi M, Khosravi‑Boroujeni H, et al. Sex based Levels of C‑reactive protein and white blood cell count In subjects with metabolic syndrome: Isfahan Healthy Heart Program. J Res Med Sci 2013;18:467‑72.
47.Khosravi‑Boroujeni H, Mohammadifard N, Sarrafzadegan N, Sajjadi F, Maghroun M, Khosravi A, Et al. Potato consumption and cardiovascular disease Risk factors among Iranian population. Int J Food Sci Nutr 2012;63:913‑20.
48.Khosravi‑Boroujeni H, Sarrafzadegan N, Mohammadifard N, Sajjadi F, Maghroun M, Asgari S, Et al. White rice consumption and CVD risk factors Among Iranian population. J Health Popul Nutr 2013;31:252‑61.
49. Nasri H, Motamedi P, Dehghani N, Nasri P, Taheri Z, Kinani F, et al. Vitamin D and immune system. J Renal Endocrinol 2014;1:5-7.
50. Asgary S, Kelishadi R, Rafieian‑Kopaei M, Najafi S, Najafi M, Sahebkar A. Investigation of the Lipid‑modifying and antiinflammatory effects of Cornus Mas L. supplementation on dyslipidemic children and Adolescents. Pediatr Cardiol 2013;34:1729‑35.
51. Iriti M, Faoro F. Grape phytochemicals: A bouquet Of old and new nutraceuticals for human health. Med Hypotheses 2006;67:833‑8.
52. GargA, Garg S, Zaneveld LJ, SinglaAK. Chemistry and Pharmacology of the Citrus bioflavonoid hesperidin. Phytother Res 2001;15:655‑69.
53. Rafieian‑Kopaei M, Baradaran A, Rafieian M. Plants Antioxidants: From laboratory to clinic. J Nephropathol 2013;2:152‑3.
54. Ghayur MN, Gilani AH, Afridi MB, Houghton PJ. Cardiovascular effects of ginger aqueous extract and Its phenolic constituents are mediated through multiple Pathways. Vascul Pharmacol 2005;43:234‑41.
55. Bahmani M, Vakili‑Saatloo N, Gholami‑Ahangaran M, Karamati SA, Khalil‑Banihabib E, Hajigholizadeh GH,et al. A comparison study on the anti‑leech effects of Onion (Allium cepa L) and ginger (Zingiber officinale) With levamisole and triclabendazole. J HerbMed Pharmacol 2013;2:1‑3.
56. Nasri H, Nematbakhsh M, Ghobadi SH, Ansari R, Shahinfard N, Rafieian‑kopaei M. Preventive and Curative effects of ginger extract against histopathologic Changes of gentamicin‑Induced tubular toxicity in rats.Int J Prev Med 2013;4:316‑21.
57. GitaC. Functional food attributes of n‑3 polyunsaturated And conjugated linoleic acid enriched chicken eggs. Curr Top Nutraceutical Res 2004;2:113‑21.
58. Khosravi‑Boroujeni H, Mohammadifard N, Sarrafzadegan N, Sajjadi F, Maghroun M, Khosravi A, Et al. Potato consumption and cardiovascular disease Risk factors among Iranian population. Int J Food Sci Nutr 2012;63:913‑20.
59. Li SQ, Zhang QH. Advances in the development of Functional foods from buckwheat. Crit Rev Food Sci Nutr 2001;41:451‑64.
60. Hamid AA, Luan YS. Functional properties of dietary Fiber prepared from defatted rice bran. Food Chem 2000;68:15‑9.
61. Rahimi Z, Mansouri Zaveleh O, Rahimi Z, Abbasi A. AT2R ‑1332 G: A polymorphism and diabetic Nephropathy in type 2 diabetes mellitus patients. J Renal Inj Prev 2013;2:97‑101.
62. Nasri H. Adiponectin and kidney. J Renal Endocrinol 2014;1:2-3.
63. Nasri H. On the occasion of the world diabetes day 2013; diabetes education and prevention; a nephrology Point of view. J Renal Inj Prev 2013;2:31‑2.
64. Sidhu KS. Health benefits and potential risks related To consumption of fish or fish oil. Regul Toxicol Pharmacol 2003;38:336‑44.
65. Heidarian E, Rafieian‑Kopaei M, Ashrafi K. The Effect of hydroalcoholic extract of Allium latifolium On the liver phosphatidate phosphatase and serum lipid Profile in hyperlipidemic rats. J Babol Univ Med Sci 2013;15:37‑46.
66. Willis MS, Wians FH. The role of nutrition in preventing Prostate cancer: A review of the proposed mechanism Of action of various dietary substances. Clin Chim Acta 2003;330:57‑83.
67. Shirzad H, Kiani M, Shirzad M. Impacts of tomato Extract on the mice fibrosarcoma cells. J HerbMed Pharmacol 2013;2:13‑6.
68. Stahl W, Sies H. Bioactivity and protective effects Of natural carotenoids. Biochim Biopsy Acta 2005;1740:101‑7.
69. Shirzad H, Taji F, Rafieian‑Kopaei M. Correlation Between antioxidant activity of garlic extracts and WEHI‑164 fibrosarcoma tumor growth in BALB/c Mice. J Med Food 2011;14:969‑74.
70. ShirzadH, ShahraniM, Rafieian‑KopaeiM. Comparison Of morphine and tramadol effects on phagocytic Activity of mice peritoneal phagocytes in vivo. Int Immunopharmacol 2009;9:968‑70.
71. Limer JL, Speirs V. Phyto‑oestrogens and breast Cancer chemoprevention. Breast Cancer Res 2004;6:119‑27.
72. Thomasset SC, Berry DP, Garcea G, Marczylo T, Steward WP, Gescher AJ. Dietary polyphenolic Phytochemicals – Promising cancer chemopreventive Agents in humans? A review of their clinical properties. Int J Cancer 2007;120:451‑8.
73. Li H, Wang Z, Liu Y. Review in the studies on tannins Activity of cancer prevention and anticancer. Zhong Yao Cai 2003;26:444‑8.
74. Nasri H, Sahinfard N, Rafieian M, Rafieian S, Shirzad M, Rafieian‑kopaei M. Turmeric: A spice With multifunctional medicinal properties. J HerbMed Plarmacol 2014;3:5‑8.
75. Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: Epidemiologic evidence and mechanistic basis. Pharmacol Res 2007;55:224‑36.
76. Tamadon MR, Baradaran A, Rafieian‑Kopaei M. Antioxidant and kidney protection; differential impacts Of single and whole natural antioxidants. J Renal Inj Prev 2014;3:41‑2.
51. Asadi-Samani M, Bahmani M, Rafieian-Kopaei M. The chemical composition, botanical characteristic and Biological activities of Borago officinalis: A review. Asian Pac J Trop Med 2014;7:22-8.
77. Ardalan MR, Rafieian‑Kopaei M. Antioxidant Supplementation in hypertension. J Renal Inj Prev 2014;3:39‑40.
78. Tavafi M. Diabetic nephropathy and antioxidants. J Nephropathol 2013;2:20‑7.
79. Baradaran A. Lipoprotein (a), type 2 diabetes and Nephropathy; the mystery continues. J Nephropathic 2012;1:126‑9.
80. Rahimi‑Madiseh M, Heidarian E, Rafieian‑kopaei M. Biochemical components of Berberis lycium fruit and Its effects on lipid profile in diabetic rats. J Herbed Pharmacol 2014; 3:15‑9.
81. Rafieian‑Kopaei M, Nasri H. Ginger and diabetic Nephropathy. J Renal Inj Prev 2013; 2:9‑10.
82. Behradmanesh S, Derees F, Rafieian‑Kopaei M. Effect Of Salvia officinalis on diabetic patients. J Renal Inj Prev 2013; 2:51‑4.
83. Brouns F. Soya isoflavones: A new and promising Ingredient for the health foods sector. Food Res Int 2002;35:187‑93.
84. Bahmani M, Zargaran A, Rafieian-Kopaei M, Saki M. Ethnobotanical study of medicinal plants used In the management of diabetes mellitus in the Urmia, Northwest Iran. Asian Pac J Trop Med 2014;7:348-54.
85. RoshanB, StantonRC. Astory of microalbuminuria and Diabetic nephropathy. J Nephropathol 2013;2:234‑40.
86. Tavafi M. Diabetic nephropathy and antioxidants. J Nephropathol 2013;2:20‑7.
87. Baradaran A. Lipoprotein (a), type 2 diabetes and Nephropathy; the mystery continues. J Nephropathol 2012;1:126‑9.
88. Rahimi‑Madiseh M, Heidarian E, Rafieian‑kopaei M. Biochemical components of Berberis lycium fruit and Its effects on lipid profile in diabetic rats. J HerbMed Pharmacol 2014;3:15‑9.
89. Rafieian‑Kopaei M, Nasri H. Ginger and diabetic Nephropathy. J Renal Inj Prev 2013;2:9‑10.
90. Tolouian R, T Hernandez G. Prediction of diabetic Nephropathy: The need for a sweet biomarker. J Nephropathol 2013;2:4‑5.
91. Sirtori CR, Galli C. N‑3 fatty acids and diabetes. Biomed Pharmacother 2002;56:397‑406.
92. Coleman MD, Eason RC, Bailey CJ. The therapeutic Use of lipoic acid in diabetes: A current perspective. Environ Toxicol Pharmacol 2001;10:167‑72.
93. Singh B. Psyllium as therapeutic and drug delivery Agent. Int J Pharm 2007;334:1‑14.
94. Momeni A. Serum uric acid and diabetic nephropathy. J Renal Inj Prev 2012;1:37‑8.
95. Nasri H, Rafieian‑Kopaei M. Herbal medicine and Diabetic kidney disease. J Nephropharmacol 2013;2:1‑2.
96. Kazemi S, Asgary S, Moshtaghian J, Rafieian M, Adelnia A, Shamsi F. Liver‑protective effects of Hydroalcoholic extract of Allium hirtifolium boiss. In Rats with alloxan‑induced diabetes mellitus. ARYA Atheroscler 2010;6:11‑5.
97. Gupta P, Andrew H, Kirschner BS, Guandalini S. Is Lactobacillus GG helpful in children with Crohn’s Disease? Results of a preliminary, open‑label study.
J Pediatr Gastroenterol Nutr 2000;31:453‑7.
98. Fuller R. Probiotics in human medicine. Gut 1991;32:439‑42.
99. Rafieian-Kopaei M. Identification of medicinal plants Affecting on headaches and migraines in Lorestan Province, West of Iran. Asian Pac J Trop Med 2014;7: 376-9.
100. Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, et al. Cancer chemopreventive activity Of resveratrol, a natural product derived from grapes.Science 1997;275:218‑20.
101. Rouhi-Broujeni A, Heidarian E, Darvishzadeh-Boroojeni P, Rafieian-Kopaei M, Gharipour M. Lipid lowering activity Of moringa pergerina seeds in rat: A comparison between The extract and atorvastatin. Res J Biol Sci 2013;8:150-4.
102. Nasri H, Ardalan MR, Rafieian‑Kopaei R. On the Occasion of world hypertension day 2014. J Parathyr Dis 2014;2:19‑20.
103. Caterson ID, Gill TP. Obesity: Epidemiology and Possible prevention. Best Pract Res Clin Endocrinol Metab 2002;16:595‑610.
104. Rubin SA, Levin ER. Clinical review 53: The Endocrinology of vasoactive peptides: Synthesis to Function. J Clin Endocrinol Metab 1994;78:6‑10.
105. Boozer CN, Nasser JA, Heymsfield SB, Wang V, Chen G, Solomon JL. An herbal supplement containing Ma Huang‑Guarana for weight loss: A randomized, Double‑blind trial. Int J Obes Relat Metab Disord 2001;25:316‑24.
106.Rafieian‑Kopaei M, Sewell RD. Newer antidepressants: Analgesia and relative monoamine reuptake inhibitory Potency. J Pharm Pharmacol 1994;46 Suppl 2:1088.
107. Losso JN. Targeting excessive angiogenesis with Functional foods and nutraceuticals. Trends Food Sci Technol 2003;14:455‑68.
108. Anwar F, Latif S, Ashraf M, Gilani AH. Moringa Oleifera: A food plant with multiple medicinal uses. Phytother Res 2007;21:17‑25.
109.BaradaranA, MadihiY, MerrikhiA, Rafieian‑Kopaei M, Nematbakhsh M, Asgari A, et al. Nephrotoxicity of Hydroalcoholic extract of Teucrium polium in Wistar Rats. Pak J Med Sci 2013;29:329‑33.
110. Ateyyat MA, Al‑Mazra’awi M, Abu‑Rjai T, Shatnawi MA. Aqueous extracts of some medicinal Plants are as toxic as Imidacloprid to the sweet potato Whitefly, Bemisia tabaci. J Insect Sci 2009;9:15.
111. Baradaran A. Beyond mineral metabolism, the bright Immunomodulatory effect of vitamin D in renal disease. J Nephropharmacol 2012;1:17‑8.
112.NasriH, BehradmaneshS, AhmadiA, Rafieian‑KopaeiM. Impact of oral vitamin D (cholecalciferol) replacement Therapy on blood pressure in type 2 diabetes patients; a Randomized, double‑blind, placebo controlled clinical Trial. J Nephropathol 2014;3:29‑33.
113. Nasri H, Shirzad H. Toxicity and safety of medicinal Plants. J HerbMed Plarmacol 2013;2:21‑2.
114. Heidarian E, Rafieian‑Kopaei M. Protective effect of Artichoke (Cynara scolymus) leaf extract against lead Toxicity in rat. Pharm Biol 2013;51:1104‑9.
115. Nasri H, Ahmadi A, Baradaran A, Nasri P, Hajian S, Pour‑ArianA, et al. A biochemical study on ameliorative effect of green tea (Camellia sinensis) extract against contrast media induced acute kidney injury. J Renal Inj Prev 2014;3:47‑9.
116. Moussavi MR. Osteoporosis in chronic kidney disease; a mini‑review on current knowledge. J Parathyr Dis 2013;1:5‑8.
117. Rafieian‑Kopaei M, BaradaranA, Rafieian M. Oxidative stress and the paradoxical effects of antioxidants. J Res Med Sci 2013;18:629.
118. Nasri H, Rafieian‑Kopaei M. Oxidative stress and aging prevention. Int J Prev Med 2013;4:1101‑2.
119. Rafieian‑Kopaei M, Baradaran A, Rafieian M. Plants antioxidants: From laboratory to clinic. J Nephropathol 2013;2:152‑3.
120. Heidarian E, Rafieian‑Kopaei M. Effect of silymarin on liver phoshpatidate phosphohydrolase in hyperlipidemic rats. Biosci Res 2012;9:59‑67.
121. HajivandiA, Amiri M. World Kidney Day 2014: Kidney disease and elderly. J Parathyr Dis 2014;2:3‑4.
122. Nasri H, Rafieian‑Kopaei M. Protective effects of herbal antioxidants on diabetic kidney disease. J Res Med Sci 2014;19:82‑3.
123. Nasri H, Rafieian‑Kopaei M. Tubular kidney protection by antioxidants. Iran J Public Health 2013;42:1194‑6.
124. Rafieian‑Kopaei M, Beyki A, Nasri H. Antioxidant therapy in hemodialysis patients. J Isfahan Med Sch 2013;31:1‑4.
125. Shirzad H, Burton RC, Smart YC, Rafieian-KopaeiM M, Shirzad M. Natural cytotoxicity of NC‑2+cells against the growth and metastasis of WEHI‑164 fibrosarcoma. Scand J Immunol 2011;73:85‑90.
126. AzadmehrA, Hajiaghaee R, AfshariA, Amirghofran Z, Rafieian‑Kopaei M, Darani YH, Shirzad H. Evaluation of in vivo immune response activity and in vitro anti‑cancer effect by Scrophularia megalantha. J Med Plants Res 2011;5:2365‑8.
127. Gharipour M, Ramezani MA, Sadeghi M, Khosravi A, Masjedi M, Khosravi‑Boroujeni H, et al. Sex based levels of C‑reactive protein and white blood cell count in subjects with metabolic syndrome: Isfahan Healthy Heart Program. J Res Med Sci 2013;18:467‑72.
128. Khosravi‑Boroujeni H, Mohammadifard N,
Sarrafzadegan N, Sajjadi F, Maghroun M, Khosravi A, et al. Potato consumption and cardiovascular disease risk factors among Iranian population. Int J Food Sci Nutr 2012;63:913‑20.
129.Om P Gulati, Peter Berry Ottaway. Legislation relating to nutraceuticals in the European Union with a particular focus on botanical-sourced products. Toxicol. 2006; 221:75–87.
130.Jones PJ, Asp NG, Silva P. Evidence for health claims on foods: how much is enough?Introduction and general remarks. J Nutr 2008; 138(6):1189S‐1191S.
131. PA. Nutraceutical/drug/anti‐terrorism safety assurance through traceability. Toxicology Letters 2004; 150:25‐27.
132.Zhao J. Nutraceuticals, nutritional therapy, phytonutrients, and phytotherapy for Improvement of human health: a perspective on plant biotechnology application. Recent Pat Biotechnol 2007;1(1):75‐97.
133. J, Mohajeri MH, Fowler A, Weber P. Challenges in discovering bioactives for The food industry. Curr Opin Biotechnol 2008; 19(2):66‐72.
134.Rishi RK. Nutraceutical: borderline between food and Drug. Pharma Review 2006, Available from: http://www.kppub.com/articles/herbal-safety-pharma-review-004/nutraceuticals-borderline-between-food-and-drugs.html. Accessed on date Feb 12, 2009.
135.Adelajadesoji O, Schilling Brian J. Nutraceutical: Blurring the line between food and drugs in the twenty-first Century. The Magazine of Food, Farm and Resource Issues 1999; 14: 35-40.
136.Om P Gulati, Peter Berry Ottaway. Legislation relating to Nutraceuticals in the European Union with a particular Focus on botanical-sourced products. Toxicol. 2006;221:75–87.
137.Richardson DP. Functional foods—shades of grey: an Industry perspective. Nutr. Rev. 1996; 54: 174–180.
138.Dietary Supplement Health Education Act (DSHEA) of 1994. Public Law 103–417, available from FDA website: http://www.fda.gov. GHHJ