Volume : 09, Issue : 10, October – 2022

Title:

33.PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND ANTIPYRETIC ACTIVITY OF MIMOSA PUDICA

Authors :

Shubhankar Soni*, Ms. Megha Shrivastava, Rishi Nema, Dr. Vivek Jain

Abstract :

Plants either in raw form or their isolated bioactive constituents are utilized as complementary and alternative medicine in various disorders. The present study was undertaken to evaluate in vitro antioxidant and antipyretic activities of the Hydroalcoholic extract of the leaves of Mimosa pudica. DPPH scavenging activity was measured by the spectrophotometer for ascorbic acid and hydroalcoholic extract of Mimosa pudica. The yeast-induced hyperthermia in the rat model was, therefore, employed to further investigate the antipyretic activity of mimosa pudica. Extract was administered i.p. 30 min before the injection of the pyrogen. The rectal temperature of animals was recorded at 1 h intervals for 4 h following the administration of drug or plant extract. This result seems to support the view that the plant has some influence on prostaglandin biosynthesis, since prostaglandin is believed to be a regulator of body temperature.
Key words: Mimosa pudica, Hydroalcoholic, Antioxidant and Antipyretic activity

Cite This Article:

Please cite this article in press Shubhankar Soni et al, Phytochemical Screening, Antioxidant And Antipyretic Activity Of Mimosa Pudica., Indo Am. J. P. Sci, 2022; 09(10).

References:

1. Chattopadhyay D, Arunachalam G, Ghosh L, Rajendran AB, Bhattacharya SK.Antipyretic activity of Alstonia macrophylla Wall exA. DC: An ethnomedicine of Andaman Islands. Journal of Pharmacy and Pharmaceutical Science. 2005; 8:558-564.
2. Spacer CB, Breder CD. The neurologic basic of fever. New England Journal of Medicine. 1994; 330:1880-1886.
3. Veugelers PJ, Kaldor JM, Strathdee SA, Page-Shafer KA, Schechter MT, Coutinho RA, Keet, IP Van Grienseven GJ. Incidence and prognostic significance of symptomatic primary human immuno deficiency virus type Infection in homosexual men. Journal of Infectious Disease. 1997; 176:112-117.
4. Eskerud JRLaerum EFagerthun HLunde PK Naess AA Fever in general practice, I: frequency and diagnosis Fam Pract 1992;9263- 269.
5. Baucher RGreen-Hernandez CedSingleton JKedAronzon DZed Fever: approach to the febrile child Primary Care Pediatrics. Philadelphia, Pa Lippincott Williams & Wilkins2001;343- 357
6. Guton H Human Physiology and Mechanisms of Disease 6th ed. Philadelphia, Pa WB Saunders1997;
7. Baraff LJBass JWFleisher GR et al. Agency for Health Care Policy and Research, Practice guideline for management of infants and children 0 to 36 months of age with fever without source Ann Emerg Med 1993;221198- 1210
8. Mukherjee PK. Quality Control of Herbal Drugs, 2nd Edition, Business Horizons, 2007; 2-14.
9. Kokate CK. Ed. Practical Pharmacognosy, 4th Edn., Vallabh Prakashan: 1994; 112:120.
10. Arpana Gaur Mishra, Richa Singh, Neha Patil, Geeta Parkhe. Determination of total phenolic, flavonoid content, antioxidant and antimicrobial activity of gloriosa superba seed extract. Asian Journal of Pharmaceutical Education and Research. 2017, 6(2):12-17.
11. Geeta Parkhe, Deepak Bharti. In vitro antioxidant activity, total phenolic and flavonoid contents of hydroalcoholic extract of leaves of Lagerstroemia Parviflora Roxb. Journal of Drug Delivery & Therapeutics. 2019; 9(4):708-711.
12. Teotino UM, Friz LP, Gandini A, Bella DD. 1963. Thio derivative of 2,3-dihydro-4H-1,3-benzoxazin-4-one syntheses and pharmacological properties. J Med Chem 6: 248–250.