Volume : 09, Issue : 09, September – 2022

Title:

12.PREVALENCE OF CARDIOVASCULAR DISEASES AND RISK-ASSESSMENT IN THE URBAN POPULATION OF PAKISTAN: A CROSS-SECTIONAL STUDY

Authors :

Dr. Ashraf Chaudhry, Dr. Shafaq Ismail, Dr. Shaiza Ijaz, Dr. Yumna Razzaq, Momina Qaisar, Mehreen Shakeel

Abstract :

Background: Non-communicable diseases are on a rise, with a major shift of trend from communicable to non-communicable diseases, amongst which, cardiovascular diseases are noticed to be escalating.
Objective: To investigate the prevalence of cardiovascular disease in Pakistan, as well as to observe frequently found risks factors and their association with CVD.
Methods: Cross-sectional study including 150 participants. Data was obtained via a self-filled online questionnaire that included anthropometric measurements, past medical history, family history and personal history comprising of smoking and drug history, level of daily exercise, food preferences and stress levels.
Results: 68.7% of the study population was female while 31.3% was male with the mean age of study participants being 30.30±13.01 years. Among 2.7% of the study population cardiovascular diseases were prevalent. Association of various risk factors with heart disease was present. Smokers (p=0.001), smokeless tobacco smokers (p=0.001), people with family history of heart disease (p=0.001), hypertensive (p=0.027), hypercholesterolemics (p=0.001) and people with higher age were shown to have an increased risk for cardiovascular disease compared with participants without heart disease. In addition to that, cardiovascular diseases were more prevalent in females with higher waist circumference (p=0.025).
Conclusion: The study concluded that there was significant correlation between cardiovascular diseases and older age, positive family history and medical history like hypertension, high cholesterol levels, as well as an association with tobacco was present. This study not only observed the prevalence of cardiovascular diseases but it also looked into the risk factors commonly found and their correlation with cardiovascular diseases.
Keywords: Non-communicable diseases, communicable diseases, cardiovascular diseases, hypertension, hypercholesterolemics.

Cite This Article:

Please cite this article in press Shafaq Ismail et al, Prevalence Of Cardiovascular Diseases And Risk-Assessment In The Urban Population Of Pakistan: A Cross-Sectional Study., Indo Am. J. P. Sci, 2022; 09(9).

Number of Downloads : 10

References:

1) Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. The lancet. 2006 May 27;367(9524):1747-57.
2) Abegunde DO, Mathers CD, Adam T, Ortegon M, Strong K. The burden and costs of chronic diseases in low-income and middle-income countries. The Lancet. 2007 Dec 8;370(9603):1929-38.
3) World Health Organization. www. who. int/en/news‐room/fact‐sheets/detail/cardiovascular‐diseases‐(cvds).
4) Jokinen E. Obesity and cardiovascular disease. Minerva pediatrica. 2014 Nov 11;67(1):25-32.
5) Wannamethee SG, Whincup PH, Shaper G, Walker M. Influence of fathers’ social class on cardiovascular disease in middle-aged men. The Lancet. 1996 Nov 9;348(9037):1259-63.
6) Mackenbach JP, Cavelaars AE, Kunst AE, Groenhof F. Socioeconomic inequalities in cardiovascular disease mortality. An international study. European heart journal. 2000 Jul 1;21(14):1141-51.
7) Ahmed ST, Rehman H, Akeroyd JM, Alam M, Shah T, Kalra A, Virani SS. Premature coronary heart disease in South Asians: burden and determinants. Current atherosclerosis reports. 2018 Jan;20(1):1-8.
8) Kamble PH, Rode MV, Phatak MS, Tayade P. Is smokeless tobacco use a risk factor for coronary artery disease? A comparative study of smokers and smokeless tobacco users. Indian Journal of Basic & Applied Medical Research. 2011;1:22-30.
9) World Health Organization. The Asia-Pacific perspective: redefining obesity and its treatment.
10) Del Pinto R, Grassi G, Ferri C, Pengo MF, Lombardi C, Pucci G, Salvetti M, Parati G. Diagnostic and Therapeutic Approach to Sleep Disorders, High Blood Pressure and Cardiovascular Diseases: A Consensus Document by the Italian Society of Hypertension (SIIA). High Blood Pressure & Cardiovascular Prevention. 2021 Mar;28(2):85-102.
11) Samuel P, Antonisamy B, Raghupathy P, Richard J, Fall CH. Socio-economic status and cardiovascular risk factors in rural and urban areas of Vellore, Tamilnadu, South India. International journal of epidemiology. 2012 Oct 1;41(5):1315-27.
12) Mendis S, Lindholm LH, Mancia G, Whitworth J, Alderman M, Lim S, Heagerty T. World Health Organization (WHO) and International Society of Hypertension (ISH) risk prediction charts: assessment of cardiovascular risk for prevention and control of cardiovascular disease in low and middle-income countries. Journal of hypertension. 2007 Aug 1;25(8):1578-82.
13) Gowshall M, Taylor-Robinson SD. The increasing prevalence of non-communicable diseases in low-middle income countries: the view from Malawi. Int J Gen Med. 2018 Jun 28;11:255-264.
14) Jafar TH, Haaland BA, Rahman A, Razzak JA, Bilger M, Naghavi M, Mokdad AH, Hyder AA. Non-communicable diseases and injuries in Pakistan: strategic priorities. Lancet. 2013 Jun 29;381(9885):2281-90.

15) Jafar TH, Jafary FH, Jessani S, Chaturvedi N. Heart disease epidemic in Pakistan: women and men at equal risk. Am Heart J. 2005 Aug;150(2):221-6.
16) Hajar R. Risk Factors for Coronary Artery Disease: Historical Perspectives. Heart Views. 2017 Jul-Sep;18(3):109-114.
17) Stewart J, Manmathan G, Wilkinson P. Primary prevention of cardiovascular disease: A review of contemporary guidance and literature. JRSM Cardiovasc Dis. 2017 Jan 1;6:2048004016687211. doi: 10.1177/2048004016687211. PMID: 28286646; PMCID: PMC5331469.

18) Mora S, Yanek LR, Moy TF, Fallin MD, Becker LC, Becker DM. Interaction of body mass index and framingham risk score in predicting incident coronary disease in families. Circulation. 2005 Apr 19;111(15):1871-6.

19) Ordovas JM, Wilson PW, Salem DN, Genest JJ, Schaefer EJ. Familial Lipoprotein Disorders In patients with premature coronary artery disease. InDrugs Affecting Lipid Metabolism 1993 (pp. 365-374). Springer, Dordrecht.

20) Genest Jr JJ, Martin-Munley SS, McNamara JR, Ordovas JM, Jenner J, Myers RH, Silberman SR, Wilson PW, Salem DN, Schaefer EJ. Familial lipoprotein disorders in patients with premature coronary artery disease. Circulation. 1992 Jun;85(6):2025-33.

21) Primrose ED, Savage JM, Boreham CA, Cran GW, Strain JJ. Cholesterol screening and family history of vascular disease. Archives of disease in childhood. 1994 Sep 1;71(3):239-42.

22) Jeppesen J, Hein HO, Suadicani P, Gyntelberg F. Relation of high TG–low HDL cholesterol and LDL cholesterol to the incidence of ischemic heart disease: An 8-year follow-up in the Copenhagen male study. Arteriosclerosis, thrombosis, and vascular biology. 1997 Jun;17(6):1114-20.

23) Shahid SU, Sarwar S. The abnormal lipid profile in obesity and coronary heart disease (CHD) in Pakistani subjects. Lipids in health and disease. 2020 Dec;19(1):1-7.

24) Flint, Alan J et al. “Body mass index, waist circumference, and risk of coronary heart disease: a prospective study among men and women.” Obesity research & clinical practice vol. 4,3 (2010): e171-e181. doi:10.1016/j.orcp.2010.01.001

25) Williams, Paul T. “Changes in body weight and waist circumference affect incident hypercholesterolemia during 7 years of follow-up.” Obesity (Silver Spring, Md.) vol. 16,9 (2008): 2163-8. doi:10.1038/oby.2008.299

26) Ghorpade AG, Shrivastava SR, Kar SS, Sarkar S, Majgi SM, Roy G. Estimation of the cardiovascular risk using World Health Organization/International Society of Hypertension (WHO/ISH) risk prediction charts in a rural population of South India. International Journal of Health Policy and Management. 2015 Aug;4(8):531.