Volume : 09, Issue : 09, September – 2022
Title:
19.AN OVERVIEW ON EMULGEL
Authors :
Arjun S. Halwai, Dr. P. S. Kawtikwar
Abstract :
Topical drug delivery system can be defined as direct effects of formulation or drug containing medication to the skin to get localizing effect of drug or directly cure cutaneous disorders. Emulgels has to be used as a topical drug delivery system for hydrophobic drugs. When gels and emulsions are used in combined form the dosage forms are referred as emulgels. Emulgels have emerged as one of the most interesting topical delivery system as it has dual release control system i.e. gel and emulsion. The major objective behind this formulation is delivery of hydrophobic drugs to systemic circulation via skin. In recent years, there has been great interest in the use of novel polymers which can function as emulsifiers and thickeners because the gelling capacity of these compounds allows the formulation of stable emulsions and creams by decreasing surface and interfacial tension and at the same time increasing the viscosity of the aqueous phase. In fact, the presence of a gelling agent in the water phase converts a classical emulsion into an emulgel. Emulgels for dermatological use have several favourable properties such as being thixotropic, greaseless, easily spreadable, easily removable, and emollient, no staining, water-soluble, longer shelf life, and bio-friendly, transparent & pleasing appearance. These emulgels are having major advantages on novel vesicular systems as well as on conventional systems in various aspects. Various permeation enhancers can potentiate the effect. So emulgel formulations can be used as better topical drug delivery systems over present conventional systems available in market.
Keywords: Topical drug delivery system, Emulgels, Hydrophobic drugs, Gelling agents, enetration enhancers.
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Cite This Article:
Please cite this article in Arjun S. Halwai et al, An Overview On Emulgel., Indo Am. J. P. Sci, 2022; 09(9).
Number of Downloads : 10
References:
1. Purushottam Sonaje Sumeet, Bhaskarrao Gondkar Sheetal, Bhandudas Saudagar Ravindra., 2013. Gellified Emulsion: A New Born Formulations For Topical Delivery of Hydrophobic Drugs A Review, World Journal of Pharmacy and Pharmaceutical Sciences, 3(1), pp 233-251.
2. Shah A. Arpan, Kamdar Kamal, Shah Rushabh, Keraliya A. Rajesh., 2013. Emulgel: A Topical Prepartions for Hydrophobic Drugs. Ph Tech Med, 2(5), pp 370-376.
3. Bhatt Preeti, Gnanarajan. G, 2013. Emulgels: A Novel Formulation Approach for the Topical Delivery of Hydrophobic Drugs A Review. International Research Journal of Pharmacy, 4(2), pp 12-16.
4. Panwar AS, Upadhyay N, Bairagi M, Gujar S, Darwhekar GN, Jain D,2011. Emulgel: A Review. Asian Journal of Pharmacy and Life Science, 1(3), pp 333-343.
5. K.P. Mohammade Haneef, Sherry Easo, P.V. Hafsa, Guru Prasad Mohanta, Chandini Nayar, 2013. Emulgel: An Advanced Review. Journal of Pharmaceutical Science and Research, 5(12), pp 254-258.
6. More S, Nandgude T, Poddar S. Vesicles as a tool for enhanced topical drug delivery. Asian J Pharm 2016;10:S196-209.
7. Ashara K, Shah K. Emulgel: A novel drug delivery system. J Prev Alzheimer’ Dis 2016;26:243-9.
8. Kuller R, Saini S, Seth N, Rana AC. Emulgel: A surrogate approach for topical used hydrophobic drugs. Int J Pharm Sci 2011;1:117-28.
9. Sharma S. Topical preparations are used for the localized effects at the site of their application by virtue of drug penetration into the underlying layers of skin or mucous membranes. Pharm Rev 2008;6:278-87.
10. Dadwal M. Emulgel: A novel approach to topical drug delivery. Int J Pharm Sci 2013;4:847-56.
11. Gupta A, Mishra AK, Singh AK, Gupta V, Bansal P. Formulation and evaluation of topical gel of diclofenac sodium using different polymers. Drug Invention Today 2010; 2:250-253.
12. Rieger MM, Lachman L, Lieberman HA, Kanig JL. The Theory and Practice of Industrial Pharmacy. 3rd ed., PA Lea and Febiger, Philadelphia; 1986. pp. 502-533
13. Stanos SP. Topical Agents for the Management of Musculoskeletal Pain. J Pain Symptom Manage 2007; 33.
14. 3. Stanos SP. Topical Agents for the Management of Musculoskeletal Pain .J Pain Symptom Manage March 2007; 33.
15. Jain A, Deveda P, Vyas N, Chauhan J et al. Development Of Antifungal Emulsion Based Gel For Topical Fungal Infection(S). IJPRD 2011; 2(12).
16. Caddeo C, Sales OD, Valenti D., Inhibition of skin inflammation in mice by diclofenac in vesicular carriers: liposomes, ethosomes and PEVs, Int. J. Pharm 2013; 443:128–136.
17. Rahmani-Neishaboor E, Jallili R, Hartwell R., Topical application of a film-forming emulgel dressing that controls the release of stratifin and acetylsalicylic acid and improves/prevents hypertrophic scarring, Wound Repair Regent 2013; 21:55–65.
18. Stanos SP., Topical Agents for the Management of Musculoskeletal Pain, J Pain Symptom Manage, March 2007; 33.