Volume : 09, Issue : 09, September – 2022

Title:

26.ANTIBIOTIC PROPHYLAXIS TO PREVENT SURGICAL SITE INFECTIONS: A REVIEW

Authors :

Pradnya Deolekar, Kavitha Dongerkery, Pramila Yadav, Sandesh Deolekar, Prathmesh Deolekar

Abstract :

In the majority of SSI cases, the pathogen source is the native flora of the patient’s skin, mucous membranes, or hollow viscera. When skin is incised, underlying tissue is exposed to overlying endogenous flora.9 Most typically, aerobic gram-positive cocci such as Staphylococcus serve as the contaminant, with resistant pathogens such as methicillin-resistant S aureus (MRSA). Entry into hollow viscera exposes surrounding tissue to gram-negative bacilli such as Escherichia coli, gram-positive organisms such as enterococcus, and, occasionally, anaerobes such as Bacillus fragilis. Yeast species and viral pathogens also pose a risk.
Other sources of SSI pathogens are from distance focus such as in patients with prosthesis or implant place during the surgery, surgical personnel, operating environment, surgical tools, instruments, and materials brought to the field during an operation.

Cite This Article:

Please cite this article in Kavitha Dongerkery et al, Antibiotic Prophylaxis To Prevent Surgical Site Infections: A Review., Indo Am. J. P. Sci, 2022; 09(9).

Number of Downloads : 10

References:

1. Horan TC, Culver DH, Gaynes RP, Jarvis WR, Edwards JR, Reid CR. Nosocomial infections in surgical patients in the United States, January 1986 – June 1992. Infect Control Hosp Epidemiol 1993;14:73-80.
2. European Centre for Disease Prevention and Control (2012) Surveillance of surgical site infections in European hospitals – HAISSI protocol. Version 1.02. Stockholm: ECDC; 2012. Link: https://bit.ly/2J2Dvuz
3. Ganguly PS, Khan Y, Malik A (2000) Nosocomial Infections and hospital procedures. Indian J Commun Med Accessed.
4. WHO document on Global Guidelines For the Prevention of Surgical Site Infection. WHO Guidelines Development Group; Geneva, Switzerland; 2016;58-177.
5. Burke JF. The effective period of preventative antibiotic action in experimental incisions and dermal lesions. Surgery 1961;50:161-8.
6. Patchen Dellinger E, Gross PA, Barrett TL, Krause PJ, Martone WJ, McGowan JE Jr, et al. Quality standard for antimicrobial prophylaxis in surgical procedures. Clin Infect Dis 1994;18:422-7.
7. Dettenkofer M, Forster DH, Ebner W, Gastmeier P, Ruden H, Daschner FD. The practice of perioperative antibiotic prophylaxis in eight German hospitals. Infection 2002;30:164-7.
8. Patchen Dellinger E, Gross PA, Barrett TL, Krause PJ, Martone WJ, McGowan JE Jr, et al. Quality standard for antimicrobial prophylaxis in surgical procedures. Clin Infect Dis 1994;18:422-7.
9. Wiley AM, Ha’eri GB. Routes of infection. A study of using “tracer particles” in the orthopedic operating room. Clin Orthop Relat Res. 1979;139:150–155. [PubMed] [Google Scholar]
10. Schaberg DR. Resistant gram-positive organisms. Ann Emerg Med. 1994;24:462–464. [PubMed] [Google Scholar]
11. Schaberg DR, Culver DH, Gaynes RP. Major trends in the microbial etiology of nosocomial infection. Am J Med. 1991;91(3B):72S–75S. [PubMed] [Google Scholar]
12. Giamarellou H, Antoniadou A. Epidemiology, diagnosis, and therapy of fungal infec*tions in surgery. Infect Control Hosp Epidemiol. 1996;17:558–564. [PubMed] [Google Scholar]
13. Cheng G, Dai M, Ahmed S, Hao H, Wang X, Yuan Z. Antimicrobial drugs in fighting against antimicrobial resistance. Front Microbiol. 2016;7:470.
14. Salkind AR, Rao KC. Antiobiotic prophylaxis to prevent surgical site infections. Am Fam Physician 2011;83:585-90.
15. Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017. JAMA Surg. 2017;152(8):784–791. doi:10.1001/jamasurg.2017.0904
16. Munckhof W. Antibiotics for surgical prophylaxis. Aust Prescr 2005;28:38-40.https://doi.org/10.18773/austprescr.2005.030
17. McDonald M, Grabsch E, Marshall C, Forbes A. Single-versus multiple-dose antimicrobial prophylaxis for major surgery: a systematic review. Aust N Z J Surg 1998;68:388-96.
18. Srivastava SK, Srivastava R. Pharmacology for MBBS. 2nd ed. New Delhi: Avichal Publishing Company; 2021.p 578
19. Tripathi KD. Essentials of Medical Pharmacology 8th ed. New Delhi :J P Brothers Medical publishers (p) Ltd.; 2021.P. 753
20. Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J HealthSyst Pharm. 2013;70(3):195–283. doi:10.2146/ajhp120568
21. Crader MF, Varacallo M. Preoperative antibiotic prophylaxis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021
22. Bosco JA, Slover JD, Haas JP. Perioperative strategies for decreasing infection: a comprehensive evidence-based approach. Instr Course Lect. 2010;59:619-28. [PubMed]
23. Global Guidelines for the Prevention of Surgical Site Infection. Geneva: World Health Organization; 2018. Available from: https://www.ncbi.nlm.nih.gov/books/NBK536404/
24. Salm L, Marti WR, Stekhoven DJ, Kindler C, Von Strauss M, Mujagic E, Weber WP. Impact of bodyweight-adjusted antimicrobial prophylaxis on surgical-site infection rates. BJS Open. 2021 Mar 5;5(2):zraa027. doi: 10.1093/bjsopen/zraa027. PMID: 33688947; PMCID: PMC7944861.
25. Basavaraju M, Alladi A, Vepakomma D. Outcome of restricted antibiotic policy in a tertiary-level paediatric surgical unit. Afr J Paediatr Surg. 2021 Jan-Mar;18(1):28-32. doi: 10.4103/ajps.AJPS_127_20. PMID: 33595538; PMCID: PMC8109756.
26. Salman MT, Ali A, Iftakhar M, Khan SW. Surgical Site Infection and its Relation with Prophylactic Antibiotics Prescription Pattern in a Tertiary Care Hospital of North India. Int Arch BioMed Clin Res [Internet]. 2018Mar.21 [cited 2022Aug.20];4(1):152-6. Available from: https://iabcr.org/index.php/iabcr/article/view/296
27. Bharath M, Galagali JR, Mishra AK, Mallick A, Nikhilesh E. Prophylactic use of antibiotics as per SIGN 104 guidelines versus routine antibiotic prophylaxis for prevention of surgical site infection in clean and clean contaminated ENT surgical procedures: a comparative study. Int J Otorhinolaryngol Head Neck Surg 2020;6:106-11
28. Valdez TA, Marvin K, Bennett NJ, Lerer T, Nolder AR, Buchinsky FJ. Current trends in perioperative antibiotic use. Otolaryngol Head Neck Surg. 2014;152(1):63-6.
29. Treatment Guidelines for Antimicrobial Use in Common Syndromes. Indian Council of Medical Research. Department of Health Research, New Delhi, India; 2017:88-96.