Volume : 09, Issue : 09, September – 2022

Title:

36.A BRIEF REVIEW ON ANTIMICROBIAL ACTIVITY OF OXAZOLE DERIVATIVES

Authors :

Mrs. Sheeja Rekha A G , Dr. Prasobh G R, Mrs. Athira A S, Mrs. Anila Kumari V S, Mrs. Seba M C, Mrs. Gini Jameena

Abstract :

The usefulness of oxazole as intermediates for the synthesis of new chemical entities in medicinal chemistry has been increased in the past few years. Oxazole is a significant heterocyclic nucleus having a wide spectrum of biological activities which drew the consideration of researchers round the globe to synthesize various oxazole derivatives and monitor them for their various biological activities. The present review article aims to review the work reported on therapeutic potentials of oxazole scaffolds which are valuable for medical applications during new millennium.
Key Words: Oxazole, Antimicrobial activity

Cite This Article:

Please cite this article in Sheeja Rekha A G et al A Brief Review On Antimicrobial Activity Of Oxazole Derivatives., Indo Am. J. P. Sci, 2022; 09(9).

Number of Downloads : 10

References:

1. Swellmeen L (2016) 1,3-Oxazole derivatives: a review of biological activities as antipathogenic. Der Pharma Chemica 8(13):269–286.
2. Hui-ZhenZhang, Zhi-LongZhao, Cheng-HeZhou (2018) Recent advance in oxazole-based medicinal chemistry. European Journal of Medicinal Chemistry 144: 444-492.
3. Chapter 8 Oxazoles and benzoxazoles. Tetrahedron organic chemistry series 20, 2000, 321-334.
4. Xunan Zheng, Wei Liu, Dawei Zhang (2020) Recent Advances in the Synthesis of Oxazole-Based Molecules via van Leusen Oxazole Synthesis. Molecules 25, 1594.
5. J. W. Cornforth, R. H. Cornforth (1947) J. Chem. Soc., 96.
6. R. Robinson (1909) J. Chem. Soc., 95, 2167.
7. R. H. Wiley, (1945) The Chemistry of Oxazoles. Chem. Rev. 37, 401.
8. D. Van Leusen, ,O. Oldenziel, A. Van Leusen (1977) J. Org. Chem. 42, 19, 3114–3118.
9. P. Chokkappagari, S. Dandu, S. Akula, S. G. V. Ramana, P. Venkatapuram (2014) J. Heterocycl. Chem. 49, 1458 –1461.
10. Z. Li, A. Zhu, J. Yang (2012) J. Heterocycl .Chem. 49, 1458 –1461.
11. D. R. Witty, G. Walker, J. H. Bateson, P. J. O’Hanlon, R. Cassels, Bioorg. (1996) Med. Chem. Lett. 6, 1375– 1380.