Volume : 10, Issue : 01, January – 2023



Authors :

Ayushi H. Mishra*, Vikrant P. Wankhade, Nirbhay A. Suryawanshi, Pranay V. Sharma

Abstract :

Polycystic ovary syndrome (PCOS), characterized by hormonal imbalance and ovarian dysfunction, often starts during adolescence. Inconsistent diagnostic criteria, variable provider knowledge, and lack of consensus pose specific challenges for the care of women with PCOS. These factors encourage inaccurate diagnosis with both under and over diagnosis. This unfavorable diagnostic experience exasperates affected women and limits timely opportunities for intervention to minimize associated comorbidities, especially during the transition from pediatric to adult care. Recognition of these issues in the care of adolescents and women with PCOS inspired the development of the International Evidence-Based PCOS Guidelines, which emphasize the prevention, screening, and treatment of PCOS across the reproductive lifespan [8]. Diabetes, cardiovascular disease and cancer are also at the forefront of any risk assessment or comprehensive treatment strategy for these women. Lifestyle modifications including dietary changes, increased exercise and weight loss are appropriate first line interventions for many women with PCOS. Pharmaceuticals including metformin, lipid lowering agents and oral contraceptives should be tailored to the individual’s risk profile and treatment goals [2].
Key Words: PCOS, anovulation, hormonal imbalance, obesity

Cite This Article:

Please cite this article in press Ayushi H. Mishra et al, A Review On Causes, Prevention, Treatment And Consequences Of Polycystic Ovarian Syndrome., Indo Am. J. P. Sci, 2023; 10(01).

Number of Downloads : 10


1. Arezoo Moini Jazani1,2 & Hamidreza Nasimi Doost Azgomi3 & Alireza Nasimi Doost Azgomi3 & Ramin Nasimi Doost Azgomi1,2 A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS) DARU Journal of Pharmaceutical Sciences (2019) 27:863–877
2. Gordon W Bates And Richard S Legro Obstetrics and Gynecology, 10390 Women and Infants Center, Birmingham, AL 35249-7333,United States Long-term management of polycystic ovarian syndrome (PCOS). Published in final edited form as: Mol Cell Endocrinol. 2013 July 5; 373(0): 91–97. Doi: 10.1016/j.mce.2012.10.029.
3. Renato Pasquali*, Elisabet Stener-Victorin, Bulent O. Yildiz, Antoni J. Duleba, Kathleen Hoeger Helen Mason, Roy Homburg, Theresa Hickey, Steve Franks, Juha S. Tapanainen, Adam Balen, David H. Abbott, Evanthia Diamanti-Kandarakis and Richard S. Legro PCOS Forum: research in polycystic ovary syndrome today and Tomorrow Published in Clinical Endocrinology (2011) 74, 424–433
4. Seema Patel Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle Endocrinopathy Published in Bioinformatics and Medical Informatics Research Center, San Diego State University, Campanile Dr, San Diego, CA, 92182, USA
5. Caroline Anne Smith3 and Alan Bensoussan3 Herbal medicine for the management of polycystic Ovary syndrome (PCOS) and associated oligo/Amenorrhoea and hyperandrogenism; a review of The laboratory evidence for effects with Corroborative clinical findings Susan Arentz, Jason Anthony Abbott2 Published in Arentz et al. BMC Complementary and Alternative Medicine 2014, 14:511
6. Robert A. Wild Long-term health consequences of PCOS Published in Human Reproduction Update, Vol.8, No.3 pp. 231±241, 2002
7. Nida Ajmal, Sanam Zeib Khan, Rozeena Shaikh Human Reproduction Update, Vol.8, No.3 pp. 231±241, 2002 Published in European Journal of Obstetrics & Gynecology and Reproductive Biology: X 3 (2019) 100060
8. Selma Feldman Witchel, Helena J. Teede2,3 and Alexia S. Peña4 Curtailing PCOS Published in Pediatric Research (2020) 87:353–361
9. Robert L. Rosenfield and David A. Ehrmann The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited Endocrine Reviews, October 2016, 37(5):467–520
10. Robert L. Rosenfield and David A. Ehrmann The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited Section of Adult and Pediatric Endocrinology, Diabetes, and Metabolism, The University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637
11. Annamaria Colao, Ulrike Blume Peytavi, Suman Rice, Asjid Qureshi, Laura Pellatt, Francesco Orio, Stephen L. Atkining Ltd Polycystic ovary syndrome (PCOS) trilogy: a translational and clinical review Helen Mason, Clinical Endocrinology (2008) 69, 831–844
12. Polycystic Ovarian Syndrome – Cleveland clinic
13. An updated overview of Polycystic Ovarian Syndrome – Ranjan Singh, Ajay Garg.
14. Anderson, T.J., Uehata, A., Gerhard, M.D., Meredith, I.T., Knab, S., Delagrange, D., Lieberman, E.H., Ganz, P., Creager, M.A., Yeung, A.C. et al. (1995) Close relation of endothelial function in the human coronary and peripheral circulations. J. Am. College Cardiol., 26, 1235±1241.
15. Anderson, K.E., Anderson, E., Mink, P.J., Hong, C.P., Kushi, L.H., Sellers, T.A., Lazovich, D. and Folsom, A.R. (2001) Diabetes and endometrial cancer in the Iowa Women’s Health Study. Cancer Epidemiol. Biomarkers Prevention, 10, 611±616.
16. Anonymous (1993) Body Fat Distribution and Risk for Death in Older Women. ACP J. Club, v119, 28-Aug.
17. Anonymous (1996) Increased body mass index predicted mortality in women. ACP J. Club, v124, 50-April.
18. Anonymous (1999) Review: glucose levels are associated with cardiovascular risk in persons without diabetes mellitus. ACP J. Club, v131, 23-Aug.
19. Balletshofer, B.M., Rittig, K., Enderle, M.D., Volk, A., Maerker, E., Jacob, S., Matthaei, S., Rett, K. and Haring, H.U. (2000) Endothelial dysfunction is detectable in young normotensive ®rst-degree relatives of subjects with type 2 diabetes in association with insulin resistance. Circulation, 101, 1780±1784.
20. Bengtsson, C., Bjorkelund, C., Lapidus, L. and Lissner, L. (1993) Associations of serum lipid concentrations and obesity with mortality in women: 20 year follow up of participants in prospective population study in Gothenburg, Sweden. Br. Med. J., 307, 1385±1388.
21. Birdsall, M.A., Farquhar, C.M. and White, H.D. (1997) Association between polycystic ovaries and extent of coronary artery disease in women having cardiac catheterization. Annals Internal Med., 126, 32±35.