Volume : 10, Issue : 03, March – 2023

Title:

20.A REVIEW ON NOVEL DRUG DELIVERY SYSTEM OF HERBAL FORMULATIONS.

Authors :

C.Mohana, Dayala. Thanusha, A. Vaishnavi , M. Kishore Babu

Abstract :

A simple and selective LC method is described for the determination of Ulipristal in tablet dosage forms. Chromatographic separation was achieved on a c18 column using mobile phase consisting of a mixture of Phosphate buffer(KH2PO4) pH4.0: Acetonitrile (30:70v/v/v),with detection of 223 nm. Linearity was observed in the range 60-140 µg /ml for Ulipristal (r2 =0.999) for drugs estimated by the proposed methods was in good agreement with the label claim. From the above experimental results and parameters it was concluded that, this newly developed method for the simultaneous estimation of Ulipristal was found to be simple, precise, accurate and high resolution and shorter retention time makes this method more acceptable and cost effective and it can be effectively applied for routine analysis in research institutions, quality control department in meant in industries, approved testing laboratories, bio-pharmaceutical and bio-equivalence studies and in clinical pharmacokinetic studies in near future.
Keywords: Ulipristal, RP-HPLC, Development, Validation

Cite This Article:

Please cite this article in press C.Mohana et al, A Review On Novel Drug Delivery System Of Herbal Formulations.,Indo Am. J. P. Sci, 2023; 10(03).

Number of Downloads : 10

References:

1. Cott J. Natural product formulations available in Europe for psychotropic indications. Psychopharmacol Bull, ; 199531:745.
2. Atram S. Recent development of herbal formulation-a novel drug delivery system. International Ayurvedic Medical Journal, 2014; 2(6):952-58.
3. Alexis F, Basto P, Levy NE, Radovic MAF, Zhang LF, Pridgen E, et al. HER-2-Targeted Nanoparticle AntiibodyBioconjugates for Cancer Therapy. Chem Med Chem, 2008; 3:1839- 43.
4. Atmakuri LR, Dathi S. Current trends in herbal medicines. J Pharm Res., 2010; 3:109-113.
5. Niculescu-Duvaz I, Springer CJ. Antibody-directed enzyme prodrug therapy (ADEPT): a review.Advanced Drug Delivery Reviews 1997; 26:151-72.
6. Manabe T, Okino H, Maeyama R, Mizumoto K, Nagai E, Tanaka M, Matsuda T. Novel strategictherapeutic approaches for prevention of local recurrence of pancreatic cancer after resection: trans tissue, sustained local drug-delivery systems. Journal of Controlled Release 2004; 100:317-30.
7. Ziaie B, Baldi A, Lei M, Gu Y, Siegel RA. Hard and Soft Micro machining for Biomems. Review of Techniques and Examples of Applications in Microfluidics and Drug Delivery. Advanced DrugDelivery Reviews 2004; 56:145-72.
8. Muller RH, Runge SA. Solid lipid nanoparticles (SLN) for controlled drug delivery. In: Benita S, editor. Submicron emulsions in drug targeting and delivery. Harwood Academic Pub, 1998; 22(7):219-234.
9. Jain NK. Controlled and Novel drug delivery, 4th edition, New Delhi: CBS Publishers and Distributers, 2002, 236- 237.
10. Patil Priyanka S, Salunkhe V.R, Magdum C.S., Mohite S.K, PHYTOSOMES: Increasing Bioavailability of Phytoconstituents. International Journal of Universal Pharmacy and Bio Sciences, 5(4): July-August 2016.
11. Vishvakrama P, Sharma S, Liposomes: An Overview. Journal of Drug Delivery and Therapeutics, 2014; 47-55.
12. Khar RK, Jain NK. Solid lipid nanoparticle as Novel Nanoparticle system in Targeted and controlled drug delivery. IJPR, 102-103.
13.Bhattacharya S. Phytosomes: Emerging Strategy in Delivery of Herbal Drugs and Nutraceuticals. Pharma Times, 2009; 41: 9–12.
14. Semalty A, Semalty M, Singh D. Supramolecular phospholipid polyphenolics interaction: The phytosome strategy to improve the bioavailability of phytochemicals. J Incl Phenom Macrocycl Chem, 2010; 67: 253-60.
15. Yue PF, Yuan HL, Li XY, Yang M, Zhu WF. Process optimization, characterization, and evaluation in vivo of Oxymatrine-phospholipid complex. Int J Pharm, 2010; 387: 139-46.
16. Das MK, Senapati PC. Furosemide loaded alginate microspheres prepared by ionic cross-linking technique: Morphology and release characteristics. Indian J Pharm Sci., 2008; 70: 77-84.
17. Jain Shikha, Jain Vikas and Mahajan S. C., Lipid Based Vesicular Drug Delivery Systems. Volume 2014 (2014), Article ID 574673, 12 pages
18. Medina OP, Zhu Y, Kairemo K. Curr Pharm Des., 2004; 10: 2981–9.
19. Akbarzadeh Abolfazl, Rezaei-Sadabady Rogaie, Davaran Soodabeh, Sang Woo Joo, Zarghami Nosratollah, Hanifehpour Younes et al. Liposome: classification, preparation, and applications. Nanoscale Res Lett. 2013 Feb 22
20. Saraf AS. Applications of novel drug delivery system for herbal formulations. Fitoterapia, 2010; 81: 680-89.
21. Hong W, Chen DW, Zhao XL, Qiao MX, Hu HY. Preparation and study in vitro of long-circulating nanoliposomes of curcumin.
22. Soppimath KS, Aminabhavi TM, Kulkarni AR, Rudzinski WE. Biodegradable polymericnanoparticles as drug delivery devices. Journal of Controlled Release, 2001; 70:1-20.
23. Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. Recent advances on chitosan-based micro andnanoparticles in drug delivery. Journal of Controlled Release 2004; 100:5-28.
24. Talmon Yeshayahu, Prager Stephen, Statistical mechanics of microemulsions, Nature, 26 May 1977; 267: 333 – 335.
25. Scarfato P, Avallone E, Iannelli P, Aquino RP. Qucertin microsphere by solvent evaporation: preparation characterization and release behavior. J Appl Polymer Sci, 2008; 109:2994-3001.
26. Mei Z, Chen H, Weng T, Yang Y, Yang X. Solid lipid nanoparticle and microemulsion for topical delivery of triptolide. Eur J Pharm Biopharm, 2003; 56: 189-196.
27. Lawrencea MJ, Reesb GD. Microemulsion-based media as novel drug delivery systems. Adv Drug Del Rev., 2000; 45: 89-121.
28. Yin YM, Cui FD, Mu CF, Choi MK, Kim JS, Chung SJ, Shim CK, Kim DD. Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation. J Control Release, 2009; 140: 86-94.
29. Zhang H, Cui Y, Zhu S, Feng F, Zheng X. Characterization, and antimicrobial activity of a pharmaceutical microemulsion. Int J Pharm, 2010; 395: 154-160.
30. Zoumpanioti M, Stamatis H, Xenakis A. Microemulsion-based organogels as matrices for lipase immobilization. Biotech Adv., 2010; 28: 395-406.
31. Ali J, Akhtar N, Sultana Y, Baboota S, Ahuja A. through O. Antipsoriatic microemulsion gel formulation for topical delivery of babchi oil (Psoralea coryfolia). Methods Find Exp Clin Pharmacol, 2008; 30: 1-9.
32. Chen Zhao X, Gao Z, Yang Y, Xu H, Yang X. A study of microemulsion systems for transdermal H, Chang X, Weng T, delivery of triptolide. J Control Release, 2004; 98: 427- 436.
33. Li SP, Kowalski CR, Feld KM, Grim WM, Recent Advances in Microencapsulation Technology and Equipment, 20 Oct 2008; 14: 353-376.
34. Parida K. R., Panda S.K., Ravanan Palaniyandi, Roy Harekrishna, Manickam Madhumathi, Talwar Priti, Microparticles Based Drug Delivery Systems: Preparation and Application in Cancer Therapeutics, IAAST, September 2013; 4[3]: 68-75.
35. Garg R, Gupta GD. Gastro retentive floating microspheres of Silymarin: Preparation and in vitro evaluation. Trop J Pharm Res., 2010; 9: 59-66.
36. Gangwar S, Singh S, Garg G. Ethosomes: A novel tool for drug delivery through skin. J Pharm Res., 2010; 3: 688-91.
37. Patel R, Singh SK, Singh S, Sheth NR, Gendle R. Development and characterization of curcumin loaded transferosomes for transdermal delivery. J Pharm Sci., 2009.
38. Tiwari Anupamaa, Mishra Manoj Kumar, Nayak Kania, Yadav Sunil Kumar, Shukla Ashutosh. Ethosomes: A Novel Vesicular Carrier System for Therapeutic Applications, IOSR Journal Of Pharmacy Volume 6, (Sep 2016)
39. Yaddalapudi Swarupa, Palla Gangaiah, Krishnaiah Devi bala Pujali, SOLID LIPID NANO PARTICLES, J Compr Phar, 2015; 2(4): 128-144.
40. Hunter CA. Vesicular System (Niosomes and Liposomes) for Delivery of Sodium Stibogluconate in Experimental Murine Visceral Leishmaniasis. J Pharm Pharmacol, 1988, 161-164.
41. Manach C, Scalbert A, Morand C, Remesy C and Jimenez L. Polyphenols: food sources and bioavailability. Am J ClinNutr, 2004; 79:727-747.
42. Abdelbary G, Eouani C, Prinderre P, Joachim J, Reynier J, and Piccerelle, P. Int.J. Pharm 2005; 292:1-2, 29-41.
43. Yoshio K, Masazumi K, Shuichi A, and Hiroaki N, J. Control. Release, 2005; 105(1-2):16-22.
44. Prajapati S, Maurya S, Das M, Tilak V, Verma K, & Dhakar R. Dendrimers in Drug Delivery, Diagnosis and Therapy: Basics and Potential Applications. Journal of Drug Delivery and Therapeutics, 2016; 6(1):67-92.
45. Muller Goymann CC. Physicochemical characterization of colloidal drug delivery systems such as reverse micelles, vesicles, liquid crystals and nanoparticles for topical administration. Europ J of Pharmaceutics and Biopharmaceutics, 2004; 58(1):343-356.
46. Ansari S. H., Islam Farha, Sameem Mohd. Influence of nanotechnology on herbal drugs. J Adv Pharm Technol Res. 2012 Jul-Sep.
47. Pinto JF, Site specific drug delivery systems within gastrointestinal tract: from the mouth to the colon. Int J Pharm, 2010; 395: 44-52.
48. Vyas SP & Khar RK. Targeted & Controlled Drug Delivery Novel Carrier Systems. 1st ed. New Delhi: CBS Publishers; 2002.