Volume : 10, Issue : 03, March – 2023

Title:

45.A COMPARATIVE STUDY OF DIFFERENT HERBAL OINTMENT FOR ANTIMICROBIAL ACTIVITY
‬

Authors :

P.Baskar, P.Kathirvel, M.Kural oviya, G.Priyadharshini*, P.Vaishnavi, J.karthi, M.Deepthi

Abstract :

The aim of this work was to formulate four different herbal ointments with ethanolic extract of Achyranthes aspera linn, Cymbopogon citaratus, Euphorbia hirta, Thyme vulgaris; (ii) investigate the in vitro antimicrobial activity of the formulated herbs using disc diffusion method. The antibacterial screening was done against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Aspergillus niger using sterile distilled water. Further, the physiochemical properties like colour, pH, spreadability, washability, skin irritancy, solubility, diffusion study loss of drying, and stability study were evaluated. The results showed that the ethanol extract of herbs possess activity even at low concentration and also shows maximum zone of inhibition comparable to the standard, ciprofloxacin (anti-bacterial), clotrimazole (antifungal). The solubilities and stability studies were good for all herbs.
KEYWORDS: Acyranthes aspera linn, Cymobopogon citaratus, Euphorbia hirta linn, Thyme vulgaris, Antimicrobial activity, herbal ointment, ethanolic extract,

Cite This Article:

Please cite this article in press Priyadharshini et al, A Comparative Study Of Different Herbal Ointment For Antimicrobial Activity., Indo Am. J. P. Sci, 2023; 10 (03).

Number of Downloads : 10

References:

1 Vijai Lakshmi, abbas Ali mahadi, dilutpal, Santosh Kumar Agarwal, An overview of Achyranthes aspera Linn, Journal of scientific and innovative research,11April2018: vol7(1), 27-29.
2 Prakash Negratti, Sudhir Patil and Kiran wadkar, Phytochemical profile and pharmacological aspects of Achyranthes aspera Linn – an overview, Journal of pharmaceutical research international,3july2021: 33(34B):187-206.
3 Senthil kumar raju, shridharshini kumar, Praveen sekar, maruthamuthu Murugesan, mohanapriya Karthikeyan, Anjana elampulakkadu and mythili arthanari, A comprehensive review on phytochemical of Achyranthes aspera Linn: An Indian medicinal plant, World journal of advanced research and reviews, 4May 2022: vol 14(02), 057-067.
4 S. shinde ganesh, p.s. rao, d.n. nandal, Rahul kunkulol, A review on pharmacological and phytochemical constituents of Achyranthes aspera Linn, International journal of pharmacognosy,28 Feb, vol 8(2), 58-64.
5 Dr. shristi balbhadra, Dr. Anshuman rajnala, Shubham balbhadra, Review of the ancient drug apamarga-(Achyranthes aspera), World journal of pharmaceutical research, 05june2020: vol 9, issue 7, 512-519.
6 Fegade S. A, kolhe R. C., Review on Achyranthes aspera (Amaranthaceae), Indian research of pharmacy and science,30jan2018: vol 4 (4), 1124-1131.
7 Janmajoy Banerjee, kamana Ghimire, amit kumar gupta and Prasanna dahal, Phytochemical constituents and pharmacological uses of medicinal plant, Achyranthes aspera: A review, World journal of pharmaceutical research,decmeber2014: vol4, issue 01, 470-489.
8 Oluwole Solomon oladeji, Funmilayo Enitan adelowo, David Temitope Ayodele, Kehinde Abraham odelade, 26august2019, phytochemical and pharmacological activities of Cymbopogon citratus: A review, scientific African, 2468-2276.
9 Karkala manvitha, Bhushan bidya, review on pharmacological activity of Cymbopogon citratus, international journal of herbal medicine,30 december2013: vol1(6): 5-7.
10 Negrelle,R.R.B., gomes,E.C., Cymbopogon citratus(DC.) stapf: chemical lcompsition and biological activities, revisao, 2007: vol9,n.9,80-92.
11 Christopher E Ekpenyong, ernest akpan, azah nyoh, ethnopharmacology, phytochemical, and biological activities of Cymbopogon citratus(DC.) stapf extracts, Chinese journal of natural medicines,2015: vol13(5):0321-0337.
12 Victor kuete, O.A. lawal, A.L. Ogungajo, N.O. Avoseh, I.A. Ogunwande, medicinal spices and vegetables from Africa therputic potential against metabolic, inflammatory, infectious and systemic diseases, chapter18, Cymbopogon citratus,2017: 397-423.
13 Opeoluwa Oyedeji, opeyemi avoseh pamela rungqu, benedicta nkeh-chungag,Adebola Oyedeji, Cymbopogon species; ethnopharmacology, phytochemistry and the pharmacological importance, molecules,23april2015: vol20, 7438-7453.
14 Surprodip mandal, Sirshendu chatterjee, Chandreji ghosh, Chandrima das, pranbesh ghosh, shakijit das,March Botanical description, phytochemical constituents and pharmacological properties of Euphorbia hirta Linn: a review, international journal of health sciences and research, 2019: vol (9); Issue:3 (273-286).
15 Meenakshi Vaidya, Darshika acharya, 25June2017, Anatomical study of Euphorbia hirta L, World journal of pharmaceutical research, 25june2017: vol6, issue7, 1407-1416.
16 Meenakshi Vaidya, darshika acharya, Pharmacognostic studies of Euphorbia Hirta L, World Journal of Pharmaceutical Research,21August2017 vol 6, Issue 10, 1043-1050.
17 Mohamad Sadiq A, Thirunavukkarasu P, Asha S, 25May2015, Phytochemical screening of Euphorbia hirta Linn leaf extracts, World Journal of Pharmaceutical Sciences,25May2015; vol3(6):1104-1112.
18 Eqbal M. A. Dauqan, aminah Abdullah, Medicinal and functional values of thyme (thyme vulgaris L.) herb, journal of applied biology and biotechnology, apirl2017: vol.5(02),017-022.
19 Hina javed, shazia erum, sobia tabassum, farhana ameen,An overview on medicinal importance of thyme vulgaris, Journal of Asian scientific research, 2013: vol3(10):974-982.
20 Ethan basch, Catherine Ulbricht, paul hammerness, anja bevis, David sollars, thyme (thyme vulgaris L.), thymol, Journal of herbal pharmacotherapy, 2004:vol.4(1) 49-67.
21 Swapnil dukare, prajkta gaikward, kolhe Shilpa savata, S.L. Jadhav, formulation and evaluation of polyherbal ointment, international journal of scientific and innovative research, 2017: 5(2), 63-68.
22 Yadav abhishek, samanta krishanu, formulation and evaluation of herbal ointment using Emblica officinalis extract, world journal of advanced research and reviews,02 feb2021 vol 09(02), 032-037.
23 Sankaradoss Nirmala, S. elavarasi, P. nadanasabapathi, P. pannerselvam, prashantha wangham, Saraswathi, formulation and evaluation of polyherbal ointment for the management of psoriasis, journal of pharmaceutical negative results,2022: vol 13, special issue 1, 1729-1737.
24 Kalpesh S. more, Dr. pankaj chaudhari, sachin mahajan, and Dr. Prakash pati, preliminary phytochemical investigation and antimicrobial activity of herbal ointment, world journal of pharmaceutical research,2021: vol 10, issue 7, 957-966.
25 Sirisha kalam, kasarla soujanya, porika mahendar, safia begum in vitro antioxidant, and cytotoxic activities of new herbal ointments, Indian journal of pharmaceutical education and research, 2016: vol 50, issue 2, s1-s10.
26 Shubhangi E. sawanti, Monali D. tajane, formulation and evaluation of herbal ointment containing neem and turmeric extract, journal of scientific & innovative research,2016: 5(4), 149-151.
27 Pulak majumder and susmita majumder, preparation and characterization of some herbal ointment formulation with evaluation of antimicrobial property, Indian journal of research in pharmacy and biotechnology,2013: vol 1(13), 385-390.