Volume : 10, Issue : 05, May – 2023



Authors :

Ahmed Qudoos, Aanand Kumar Lohana, FNU Saveeta, Munesh Kumar, Manisha Lohana, Pooja Bai

Abstract :

Background: The occurrence of spontaneous bacterial peritonitis (SBP) is a significant complication among patients with cirrhosis, and has been linked to renal impairment. However, there have been no studies specifically focused on this problem.
Objective: To determine the incidence and mortality rate of renal impairment after SBP in cirrhotic patients. Methodology: The study was carried out at the Department of Medicine at Liaquat University Hospital, Hyderabad, from January 2022 to July 2022, using a cross-sectional observational analysis. A sample of 291 cirrhotic patients was selected through non-probability consecutive sampling. SBP diagnosis was made when the ascitic fluid polymorphonuclear cell count was equal to or greater than 250 cells/mm³. Data was collected using a pre-structured, interview-based questionnaire containing inquiries about basic sociodemographic details, clinical examinations details, and particulars of laboratory investigation. The data was analyzed using and SPSS v. 26.0.
Results: The study found that the incidence of SBP was 23.02%, with 30 episodes (45.52%) of SBP associated with renal impairment (transient in 50.82%, steady in 21.31%, and progressive in 27.87%). The mortality rate associated with progressive renal impairment was 100%, 53.85% with steady renal impairment, and 9.68% with transient renal impairment. The mortality rate in patients with renal impairment was significantly higher than in those without (44.26% vs. 8.06%).
Conclusion: This study highlights the common occurrence of renal impairment after SBP among cirrhotic patients, and suggests that it is a poor prognostic factor for this infection.
Keywords: Liver cirrhosis, incidence rate, mortality rate, renal impairment, spontaneous bacterial peritonitis.

Cite This Article:

Please cite this article in press Ahmed Qudoos et al, Incidence And Mortality Rate of Renal Impairment after Spontaneous Bacterial Peritonitis Among Patients Suffering From Cirrhosis., Indo Am. J. P. Sci, 2023; 10 (05).

Number of Downloads : 10


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