Volume : 10, Issue : 05, May – 2023



Authors :

Suryawanshi Gajanan*, Fugate Ajay, Sameer Shafi

Abstract :

A topical gel is a circumfluous lozenge form that’s applied to the skin for the delivery of medicines. Topical gels offer several advantages as a medicine delivery system, including targeted delivery, controlled release, and reduced systemic side goods. Topical medicine delivery systems include a large variety of pharmaceutical lozenge form like semisolids, liquid medication, sprays and solid maquillages. Topical gels are stylish choice for treat original infections and skin problems because of it directly apply on the skin or in the point. Topical gels give action direct to the point of action. Topical gels count the GI vexation and metabolism of medicine by which the bioavailability of medicine is lesser. The expression and evaluation of topical gels involve careful consideration of component selection, gel medication, physical and natural characteristics, and stability. Topical gels have been delved for the treatment of a wide range of conditions, including arthritis pain, acne, and psoriasis. farther exploration is demanded to optimize the expression and estimate the efficacity of topical gels for colorful suggestions. Overall, topical gels offer a promising medicine delivery system for localized and sustained medicine delivery. The clinical substantiation indicates that topical gel is a safe and utmost effective treatment option for use in the operation of skin related complaint and used for original action to reduce the side goods associated with another conventional lozenge form.
Keywords: Topical gel, GI irritation, Bioavailability, Arthritis, Psoriasis etc.

Cite This Article:

Please cite this article in press Suryawanshi Gajanan Madhav et al, Topical Gel: – As A Drug Delivery System., Indo Am. J. P. Sci, 2023; 10 (05).

Number of Downloads : 10


1. Karanda P, Mitragotri S: Enhancement of transdermal drug delivery via synergistic action of chemicals, Biochemical et Biophysica Actas,2009, 1788:2362-2373.
2. Kumar SKP, Bhowmik D, Jaiswal J, Transdermal Iontophoresis Technique-A Potential Emerging Drug Delivery System, Indian Journal of Research in Pharmacy and Biotechnology, 1(1), 2013, 38-45.
3. Maschera, Musharraf A. Semi solid Dosage Form: Topical Gel Formulation A Review. World J Pharm Res. 2016;5(12):1256- 1268.
4. Lakshmi P K, Samarth K, D. Prasanth B. Veers, Chennai A. Oils as Penetration Enhancers for Improved Transdermal Drug Delivery: A Reviewing. Res. J. Pharm 2017; 8(4):9-17.
5. Sharma B, Singh LR. Pharmaceutical gels for topical drug delivery: An overview. Int. J Res Pharm Ceutical Sci 2018; 2:.19-24.
6. Niyaz BB, Kalyani P, Divakar G: Formulation and evaluation of gel containing fluconazole antifungal agent. International Journal of Drug Development and Research. 2011; 3(4): 109-128.
7. Jivani MN, Patel. CP, Prajapati.BG. Nanomole Innovative Approach for Topical Gel Based Formulation.2018; 1(2):18-23.
8. Bhowmik D, Scopoletin KR, Drivel S, Kumar KS, Recent Approaches in Transdermal Drug Delivery System, The Pharma-Innovation Journal, 2(3), 2013, 99-108.
9. Kaur J, Kaur J, Jaiswal S, Gupta GD. Recent advances in topical drug delivery system. Indo Am. J Pharm. 2016;6(7):2231-6876.
10. Patel HK, Dhiren P. Shah. A Review on Micro emulsion Based Gel: An Innovative Approach for Topical Delivery of Hydrophobic Drug World J Ceutical Rese 2018; 7 (7): 344- 349.
11. Goyal S, Sharma P, Ramchandani U, Shrivastava SK and Dubey PK: Novel anti-inflammatory topical gels. International Journal of Pharmaceutical and Biological Archives. 2011; 2(4): 1087-1094.
12. Pad AR, Handguide TD, Ganapathy RS et al. Emulex: A Comprehensive Review for Topical Delivery of Hydrophobic Drugs. Asian J Celtics 2018; 12(2):13-18.
13. Pandey S, Bandola A, Bhatt GK, Kothiya P, An Overview on Transdermal Drug Delivery System, Int Journal of PR and Chemical Sciences, 2(3), 2013, 1171-1180.
14. Verma A, Singh S, Kaur R, Jain U. An Overall Review on Topical Preparation-Gel. Int. J. Pharm. Sci. Rev.res. 2016;1(1):17- 20.
15. Ojha A, Ojha M, N.V. SatheeshMadhavetal.Recent Advancement in Emulex: A Novel Approach for Topical Drug Delivery. Int J Advances P’ceutics2017; 6(1):17-23.
16. Ojha A, Ojha M, N.V. Satheesh Madhava al. Recent Advancement in Emulex: A Novel Approach for Topical Drug Delivery. Int J Advances P’ceutics2017; 6(1):17-23.
17. A. KrishnaSailaja, R. Supraja.et al. An Overall Review on Topical Preparation-Gel: Innovate Int J of Medical & Ceutical Sciences 2016; 1(1): 17-20.
18. Syed Ayesha Ahmed un Nabi, Muhammad Ali Shiraz, Sofia Ahmed, Aneesa Mustang, Iqbal Ahmad.P’ceutical Gels: A Review. RADS-JPPS 2016; 1:40-48.