Volume : 11, Issue : 12, December – 2024

Title:

FROM THE GUT TO THE LIVER: EXPLORING THE GUT MICROBIOME’S IMPACT ON ALCOHOL-ASSOCIATED LIVER DISEASE

Authors :

Om Sai Srija Kancheti, Gurucharan Nagender Yarasani, Abhinaya Surabattula

Abstract :

Background: Excessive alcohol use disrupts gut bacteria, leading to liver disorders such as alcohol-associated liver disease (ALD) and cirrhosis. Advances in sequencing reveal changes in the gut microbiota related to alcohol intake, suggesting potential treatments. This review examines the complex link between gut microbiota, liver health, and alcohol consumption. It also highlights the importance of microbial-based therapies such as prebiotics, probiotics, postbiotics, and synbiotics.
Methods: We conducted a comprehensive literature review from October to November 2023. using PubMed, Google Scholar, and Google. Studies of any biological sex, ethnicity, and age were included. The studies reviewed spanned a period of 11 years from 2013 to 2024.
Conclusion: Therapeutic approaches based on microbes, such as probiotics, postbiotics, prebiotics, and synbiotics present promising treatment alternatives that could improve the management of ALD.

Keywords: Alcohol-associated liver disease, gut microbiome, prebiotics, probiotics, postbiotics, synbiotics

Cite This Article:

Please cite this article in press Murali Chand Ginjupalli et al., From The Gut To The Liver: Exploring The Gut Microbiome’s Impact On Alcohol-Associated Liver Disease. .,Indo Am. J. P. Sci, 2024; 11 (12).

Number of Downloads : 10

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