Volume : 11, Issue : 12, December – 2024
Title:
A REVIEW: PLANT-DERIVED NATURAL IMMUNOMODULATORS
Authors :
Deepthika. Patchigolla*, Udayasri. Jagabathuni , Sanmathi. Ramesh , Srikanya. Aare
Abstract :
The concept of immunomodulation, introduced by Edward Jenner in 1796, has revolutionized the treatment of autoimmune diseases, viral infections, and certain cancers. Conditions like rheumatoid arthritis, inflammatory bowel diseases, and systemic lupus erythematosus are characterized by abnormal immune responses, involving cytokines like tumor necrosis factor-α and interleukins. Immunomodulation, which modifies immune responsiveness, has led to the exploration of phytomedicines as immunostimulants or immunosuppressants. For centuries, medicinal plants have been used to alter immune systems, and recent studies have confirmed their immunomodulatory potential. This review highlights 58 plants, including Curcuma longa, Andrographis paniculata, Resveratrol, Moringa oleifera and Tinospora cordifolia, whose phytochemicals flavonoids, terpenoids, polysaccharides, and alkaloids exhibit immunomodulating properties. By integrating phytochemical, pharmacological, and therapeutic aspects, this article provides an up-to-date understanding of medicinal plants as immunomodulators, offering insights into their mechanisms of action and potential applications.
Keywords: Immunomodulators, Immunostimulants, Immunosuppressants, Traditional plants
Cite This Article:
Please cite this article in press Deepthika. Patchigolla et al., A Review: Plant-Derived Natural Immunomodulators.,Indo Am. J. P. Sci, 2024; 11 (12).
Number of Downloads : 10
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