Volume : 11, Issue : 12, December – 2024
Title:
FORMULATION AND EVALUATION OF MICROSPHERES OF NIFEDIPINE
Authors :
Mohammad Saif*, Dr. D. Venkata Ramana
Abstract :
The aim of the study was to prepare Nifedipine microspheres using Solvent evaporation method using different polymer ratio. FT-IR studies revealed that there was no chemical interaction between the drug and polymer. The average particle size of the optimized formulation was found to be 166 μm. The in-vitro release behavior from all the Nifedipine microspheres was found to be peppas drug release kinetics and produced a sustained release over a period of 12 hours with better entrapment efficiency.
Key words: Nifedipine, Eudragit, Carbopol 934p, HPMC, Solvent evaporation method and microspheres.
Cite This Article:
Please cite this article in press Mohammad Saif et al Formulation And Evaluation Of Microspheres Of Nifedipine.,Indo Am. J. P. Sci, 2024; 11 (12).
Number of Downloads : 10
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