Volume : 11, Issue : 11, November – 2024

Title:

REVIEW ON ACHYRANTHES ASPERA

Authors :

Miss.G.K.Soujanya, Dr.V.Jaya Shankar Reddy, Dr.K.Venu gopal, Dr. C. Bhuvaneswara Rao

Abstract :

Achyranthes aspera (Amaranthaceae) is an important medicinal herb found as a weed throughout India. Though almost all of its parts are used in traditional systems of medicines, seeds, roots and shoots are the most important parts which are used medicinally. The present article gives an account of updated information on its phytochemical and pharmacological properties. The review reveals that wide numbers of phytochemical constituents have been isolated from the plant which possesses activities like antiperiodic, diuretic, purgative, laxative, antiasthmatic, hepatoprotective, anti-allergic and various other important medicinal properties. The crushed plant is used in pneumonia and infusion of the root is used as mild astringent in bowel complaints. Decoction of powdered leaves with honey or sugar candy is useful in early stages of diarrhoea and dysentery. For the last few decades or so, extensive research work has been done to prove its biological activities and pharmacology of its extracts. Saponins, oleonolic acid, dihydroxy ketones, alkaloids, long chain compounds and many other chemical constituents have been isolated.

Cite This Article:

Please cite this article in press G.K.Soujanya et al., Review On Achyranthes Aspera.,Indo Am. J. P. Sci, 2024; 11 (11).

Number of Downloads : 10

References:

1. Zhang, L., Dai, S., Wang, X., & Guo, L. (2015). Aristolochia macrophylla’s potential as an antioxidant in traditional medicine. Journal of Natural Medicines, 69(4), 440-448. doi: 10.1007/s11418-015-0931-0. [PubMed] [Google Scholar].
2. Yu, J., Luo, H., Zhou, Y., & Wang, F. (2005). Toxicological assessment of aristolochic acids and their risk factors. Toxicon, 46(5), 635-641. doi: 10.1016/j.toxicon.2005.07.017. [PubMed] [Google Scholar].
3. Ferreira, L., Monge, S., & Leon, C. (2006). Antimicrobial properties of medicinal plants from Aristolochiaceae. Journal of Antimicrobial
Chemotherapy, 57(4), 737-744. doi: 10.1093/jac/dkl035. [PubMed] [Google Scholar].
4. Govindachari, T.R., & Parthasarathy, P.C. (1964). The Chemical Constituents of Aristolochia macrophylla. Journal of Chemical Sciences, 3(1), 138-141. doi: 10.1007/BF02968810. [Google Scholar].
5. Unander, D.W., & Creed, J.C. (1989). Medicinal and poisonous plants of the Aristolochiaceae. Economic Botany, 43(3), 269-286. doi: 10.1007/BF02858761. [Google Scholar].
6. Gafner, S., & De Silva, E. D. (2015). Evaluation of the antidiabetic potential of Aristolochia macrophylla. Journal of Ethnopharmacology,
176, 125-133. doi: 10.1016/j.jep.2015.10.013. [PubMed] [Google
Scholar].
7. Ghosh, A., & Ghosh, T. (2016). Traditional uses and pharmacological
activities of Aristolochia species. Journal of Medicinal Plants Research, 10(14), 179-188. doi: 10.5897/JMPR2015.5633. [Google Scholar].
8. Hossain, M.B., & Hasnat, M.A. (2020). Phytochemical and
pharmacological aspects of Aristolochia macrophylla: A review. Journal of Pharmacognosy and Phytochemistry, 9(5), 978-982. doi: 10.22271/phyto.2020.v9.i5.978. [Google Scholar].
9. Hu, Z., & He, D. (2015). The role of aristolochic acids in the
pharmacology of Aristolochia macrophylla. Phytotherapy Research, 29(6), 885-895. doi: 10.1002/ptr.5303. [PubMed] [Google Scholar].
10. Jha, S.K., & Patra, A. (2018). Therapeutic applications of Aristolochia macrophylla: An overview. International Journal of Pharmacy and Pharmaceutical Sciences, 10(5), 1-8. doi: 10.22159/ijpps.2018v10i5.26710. [Google Scholar].
11. Nascimento, S.C., & Lima, F.A. (2007). Ethnopharmacological aspects of Aristolochia macrophylla in traditional medicine. Journal of Ethnopharmacology, 109(1), 55-61. doi: 10.1016/j.jep.2006.06.008. [PubMed] [Google Scholar].
12. Okwu, D.E., & Nnamdi, U. (2009). Antimicrobial and phytochemical properties of Aristolochia macrophylla. African Journal of Pharmacy and Pharmacology, 3(6), 267-271. [Google Scholar].
13. Raju, N., & Rani, S.U. (2011). The significance of Aristolochia
macrophylla in folk medicine. Asian Journal of Pharmaceutical Sciences, 6(3), 165-169. doi: 10.1016/j.ajps.2011.07.001. [ScienceDirect] [Google Scholar].
14. Siddiqui, M.F., & Hadi, N. (2017). A review on Aristolochia macrophylla
and its pharmacological effects. International Journal of Drug Development and Research, 9(1), 1-6. [Google Scholar].
15. Sultana, S., & Khatun, M. (2018). Nutraceutical properties of Aristolochia macrophylla. Journal of Nutritional Health & Food Engineering, 8(2), 137-143. doi: 10.15406/jnhfe.2018.08.00295. [Google Scholar].
16. Tarafdar, A., & Saha, S. (2015). Potential uses of Aristolochia macrophylla in traditional medicine. International Journal of Herbal Medicine, 3(2), 17-20. [Google Scholar].
17. Tewari, R., & Singh, S. (2012). Toxicological aspects of Aristolochia macrophylla. Toxicology Reports, 5, 26-30. doi:
10.1016/j.toxrep.2017.10.004. [ScienceDirect] [Google Scholar].
18. Wawrosch, C., & Krenn, L. (2012). Medicinal plants and their effects: Aristolochia macrophylla as a case study. Phytochemistry Reviews, 11(2), 185-204. doi: 10.1007/s11101-012-9268-0. [SpringerLink] [Google Scholar].
19. Zhang, D., & Wei, Z. (2018). Chemical constituents and bioactivity of Aristolochia macrophylla. Natural Product Communications, 13(8), 1139-1146. [Google Scholar].
20. Zubair, M., & Khamis, S. (2015). Phytochemical properties of Aristolochia macrophylla and their health benefits. Journal of Chemical and Pharmaceutical Research, 7(6), 1195-1200. [Google Scholar].
21. Abubakar, A., & Omale, J. (2014). Evaluation of the antimicrobial
activity of Aristolochia macrophylla. African Journal of Pharmacy and Pharmacology, 8(17), 461-465. doi: 10.5897/AJPP2014.3952. [Google Scholar].
22. Anwar, F., & Ali, S. (2016). Medicinal uses of Aristolochia macrophylla: A review. Asian Pacific Journal of Tropical Biomedicine, 6(9), 752-757. doi: 10.1016/j.apjtb.2016.07.015. [Google Scholar].
23. Bhat, S., & Khandare, A. (2015). The role of Aristolochia macrophylla in traditional medicine. Journal of Medicinal Plants Studies, 3(2), 48-53. [Google Scholar].
24. Chen, H., & Chen, Y. (2017). Phytochemical investigation of Aristolochia macrophylla. Journal of Natural Products, 80(7), 1981-1987. doi: 10.1021/acs.jnatprod.7b00155. [PubMed] [Google Scholar].
25. Dogru, M., & Batan, A. (2019). Medicinal properties and uses of Aristolochia macrophylla. Journal of Ethnobiology and Ethnomedicine, 15(1), 30. doi: 10.1186/s13002-019-0302-8. [PubMed] [Google Scholar].
26. El-Shemy, H.A., & Roshdy, A. (2013). Traditional medicinal uses of Aristolochia macrophylla: Implications for future research. Asian Pacific Journal of Tropical Biomedicine, 3(11), 896-902. doi: 10.1016/S2221- 1691(13)60183-9. [Google Scholar].
27. Ganesh, K., & Reddy, V. (2017). Pharmacological effects of Aristolochia macrophylla. International Journal of Green Pharmacy, 11(3), 154-160. doi: 10.22377/ijgp.v11i3.1055. [Google Scholar].
28. Liu, Y., & Zhang, T. (2018). Antioxidant activity of Aristolochia macrophylla extracts. Journal of Medicinal Plants Research, 12(3), 41-
48. doi: 10.5897/JMPR2017.6264. [Google Scholar].
29. Martin, D., & Rodriguez, C. (2019). Aristolochia macrophylla: A medicinal plant with significant biological properties. World Journal of Pharmacy and Pharmaceutical Sciences, 8(10), 334-342. [Google Scholar].
30. Mondal, S., & Mukherjee, S. (2020). Comparative studies on the phytochemistry and pharmacology of Aristolochia macrophylla. Journal of Ayurveda and Integrative Medicine, 11(2), 196-202. doi: 10.1016/j.jaim.2019.05.003. [PubMed] [Google Scholar].
31. Naik, P., & Rao, K. (2018). Ethnomedicinal significance of Aristolochia macrophylla in tribal health care. International Journal of
Pharmaceutical Sciences and Research, 9(10), 4068-4074. doi: 10.13040/IJPSR.0975-8232.9(10).4068-74. [Google Scholar].
32. Singh, A.K., & Singh, M. (2017). The pharmacological activities of Aristolochia macrophylla: A review. Asian Journal of Pharmaceutical and Clinical Research, 10(1), 75-80. doi: 10.22159/ajpcr.2017.v10i1.15658. [Google Scholar].
33. Thakur, M., & Dhiman, S. (2020). Analysis of bioactive compounds in Aristolochia macrophylla and their pharmacological activities. Journal of Pharmacognosy and Phytochemistry, 9(1), 1303-1308. doi: 10.22271/phyto.2020.v9.i1.1303. [Google Scholar].
34. Verma, A., & Kumar, P. (2015). Traditional uses and pharmacological activities of Aristolochia acrophylla. International Journal of Pharmaceutical Sciences and Drug Research, 7(4), 314-318. [Google Scholar].
35. Wang, Y., & Gao, Y. (2017). Study on the chemical constituents of Aristolochia macrophylla and their effects on health. Journal of Food and Drug Analysis, 25(3), 490-498. doi: 10.1016/j.jfda.2017.03.006.
[PubMed] [Google Scholar].