Volume : 11, Issue : 10, October – 2024
Title:
FORMULATION AND EVALUATION OF ATOMOXETINE HCL SUSTAINED RELEASE TABLETS
Authors :
K.Sai Varsha*, Dr.J.Ramesh
Abstract :
The objective of the present study was to develop a sustained release matrix tablets of Atomoxetine Hcl an hyperactivity disorder. The sustained release tablets were prepared by direct compression method and formulated using different polymer ratios formulation such as AH1 to AH 9 polymers like HPMC K100M ,Ethyl cellulose and Xanthan gum were used compatibility of the drug with various excipients was studied. The compressed tablets were evaluated and showed compliance with pharmacopoeial limits. The optimized formulation AH4 on basis of acceptable tablet properties and in vitro drug release . The resulting formulation produced robust tablets optimum hardness, consistent weight uniformity and friability . All tablets were sustained release for Atomoxetine Hcl for 12hrs among all the nine formulations AH4 showed 99.23% for 12hrs and consider as a optimized formulation.
Keywords: Atomoxetine Hcl , sustained release tablets
Cite This Article:
Please cite this article in press K.Sai Varsha et al Formulation And Evaluation Of Atomoxetine Hcl Sustained Release Tablets.,Indo Am. J. P. Sci, 2024; 11 (10). .
Number of Downloads : 10
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