Volume : 11, Issue : 10, October – 2024

Title:

FORMULATION, DEVELOPMENT, AND IN-VITRO EVALUATION OF ORALLY DISINTEGRATING TABLETS OF ISOSORBIDE MONONITRATE

Authors :

D.Swetha*, Shaik Zareena Begum,B.Thejovathi

Abstract :

The present study was carried out to develop Oral Disintegration Tablets of Isosorbide Mononitrate. Ac-Di-Sol ,PolyPlasdoneXl, and Tulsion 339 were used as super disintegrants. The drug –excipients interaction was investigated by FTIR. The blend of all the formulations showed good flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. Among all the formulations F9 showed maximum % drug release i.e., 99.01% in 30 min hence it is considered as optimized formulation.
Keywords : Isosorbide Mononitrate, Ac-Di-Sol, Poly PlasdoneXl, Tulsion 339 and Oral disintegrating tablets.

Cite This Article:

Please cite this article in press D.Swetha et al Formulation, Development, And In-Vitro Evaluation Of Orally Disintegrating Tablets Of Isosorbide Mononitrate..,Indo Am. J. P. Sci, 2024; 11 (10).

Number of Downloads : 10

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