Volume : 12, Issue : 04, April – 2025

Title:

ASSESSING EFFICACY OF COMBINED EXTRACT OF TAMARINDUS INDICA SEEDS AND CURCUMA LONGA RHIZOMES ON ANTI-ARTHRITIC ACTIVITY

Authors :

Venkata lakshmi Alluri, Jyothi Prasanna. Alajangi, Indu Sri Priya. Allada,Sai Sri Durga. Allapalli, Srinivas. Kolli, Narendra. Devaboyina

Abstract :

Knee pain is a common condition that effects people of all ages. Knee pain may be the result of an injury such as a ruptured ligament or cartilage. Rheumatoid arthritis is the most common reason for physical disability along with the age. Herbal cream is an anti-inflammatory formulation which contains ethanolic extract of Tamarindus indica and ethanolic extract of Curcuma longa rhizomes.
The study investigates the efficacy of a topical herbal cream in managing knee joint pain, exploring its potential to alleviate pain and inflammation associated with conditions like Osteoarthritis, by utilizing a blend of natural plant extracts known for their Anti-inflammatory and analgesic properties, applied directly to the affect knee area, aiming to provide a safe and well-tolerated alternative pain management strategy compared to conventional pharmaceutical treatments.
The intervention is a cream formulated with a combination of herbal extracts believed to have anti-inflammatory and pain-relieving properties The cream is applied directly to the knee joint. Allowing the active ingredients to penetrate the skin and potentially act locally to reduce pain and inflammation. The study aims to demonstrate the effectiveness of the herbal cream in managing knee pain, potentially offering a natural alternative with minimal side effects.
KEY WORDS: Anti-inflammatory, Herbal cream, Management, Rheumatoid arthritis

Cite This Article:

Please cite this article in press Venkata Lakshmi Alluri et al., Assessing Efficacy Of Combined Extract Of Tamarindus Indica Seeds And Curcuma Longa Rhizomes On Anti-Arthritic Activity., Indo Am. J. P. Sci, 2025; 12(04).

Number of Downloads : 10

References:

1. Peat G, McCarney R, Croft P. Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis. 2001; 60: 91-97.
2. O’Reilly S. Occupation and knee pain: a community-based study. Osteoarthritis Cart. 2000; 8: 78–81.
3. Toda Y, Tsukimura N. A six-month follow up of a randomized trial comparing the efficacy of a lateral-wedge insole with subtalar strapping and an in-shoe lateral-wedge insole in patients with varus deformity osteoarthritis of the knee. Arthritis Rheum. 2004; 50: 3129-3136.
4. Holden MA, Nicholls EE, Young J, et al. Role of exercise for knee pain: what do older adults in the community think? Arthritis Care Res. 2012; 64: 1554-1564.
5. Hendry M, Williams NH, Markland D, et al. Why should we exercise when our knees hurt? A qualitative study of primary care patients with osteoarthritis of the knee. Fam Pract. 2006; 23: 558-567.
6. Park Y, Chang M (January 2016). “Effects of rehabilitation for pain relief in patients with rheumatoid arthritis: a systematic review”. Journal of Physical Therapy Science. 28 (1): 304–308.
7. Böhler C, Radner H, Smolen JS, Aletaha D (2013) Serological changes in the course of traditional and biological disease modifying therapy of rheumatoid arthritis. Ann Rheum Dis 72(2):241–244.
8. Rausch Osthoff AK, Juhl CB, Knittle K, Dagfinrud H, Hurkmans E, Braun J, Schoones J, Vliet Vlieland TP, Niedermann K (2018-12-04). “Effects of exercise and physical activity promotion: meta-analysis informing the 2018 EULAR recommendations for physical activity in people with rheumatoid arthritis, spondyloarthritis and hip/knee osteoarthritis”. RMD Open. 4 (2): e000713.
9. Rombouts Y, Willemze A, van Beers JJ, Shi J, Kerkman PF, van Toorn L, Pruijn GJ (2016) Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis. Ann Rheum Dis 75(3):578–585.
10. Yarwood A, Viatte S, Okada Y, Plenge R, Yamamoto K, BRAGGSS, R, Klareskog L (2016) Loci associated with N- glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study. Ann Rheum Dis 75(1):317–320.