Volume : 12, Issue : 04, April – 2025

Title:

OVERVIEW OF VARIOUS PHYTOCONSTITUENTS & PHARMACOLOGICAL ACTIVITY OF POTENTIAL PLANT ECHINOPUS ECHINATUS PLANT

Authors :

Shrihari V Nighot *, Radhesham A. Tekale, Ankita S. Jadhav, Swati P. Deshmukh

Abstract :

Echinops echinatus emerges as a promising plant with a rich profile of phytoconstituents contributing to various pharmacological activities. Its diverse benefits—including antioxidant, anti-inflammatory, antimicrobial, analgesic, and antidiabetic properties—underline its potential applications in modern therapeutics. Continued research into its mechanisms of action and clinical efficacy could facilitate the development of new herbal medications, promoting its integration into conventional medical practices. The exploration of Echinops echinatus not only enhances our understanding of traditional medicine but also opens avenues for innovative treatments based on natural compounds. Echinops echinatus has considerable potential as a medicinal plant due to its rich array of phytoconstituents and documented pharmacological activities. Further research is warranted to explore its therapeutic efficacy and mechanisms of action, with a focus on clinical trials to validate its uses in modern medicine. The findings underscore the importance of integrating traditional knowledge with scientific investigation to promote the use of Echinops echinatus as a viable natural therapeutic agent.

Cite This Article:

Please cite this article in press Shrihari V Nighot et al Overview Of Various Phytoconstituents & Pharmacological Activity Of Potential Plant Echinopus Echinatus Plant .,, Indo Am. J. P. Sci, 2025; 12(04).

Number of Downloads : 10

References:

1. Khan, M. I., et al. (2015). “Phytochemical and pharmacological aspects of Echinops echinatus: A review.” International Journal of Pharmacognosy and Phytochemical Research.
2. Sahu, P. K., et al. (2020). “Echinops echinatus: A comprehensive review on its phytochemistry and medicinal properties.” Journal of Herbal Medicine.
3. Jabbar, A., et al. (2017). “A review on Echinops echinatus: Phytochemistry and pharmacological properties.” Pharmacognosy Reviews.
4. Swain Pramod Kumar, Nayak Durga Prasan. Development & Evaluation of Poly Herbal Syrup from Some Herbs Used As Expectorant. W J Pharm & Pharma Sci 2013: 2(5):3449
5. Niharika Sahoo, et al. Herbal drug patenting in India: IP potential .N Sahooet al. J Ethnopharmacol 2011;(137):289-290
6. Satyajit D. Sarker, et al. Gray Natural products isolation second edition 2006 humana Press Inc.
7. Hedge, I. C., Echinops L. Flora of Turkey and the East Aegean Islands, (Ed. P. H. Davis) vol 5, 609-622, Edinburgh University Press, Edinburgh, 1975.
8. Evans W. C: Trease and Evans Pharmacognosy (16th ed.); Elsevier: Science limited, UK, (2009), pp. 353-56.
9. Indian Medicinal Plants, By Kritikar K. R. & Basu B. D., Plate volume (3), Second edition, Page No.548.
10. Abdulrazzaq H. M, Kadeem J. E, Al-Mohannadi S. S: Hepatoprotective effect of Echinops tenuisectus (Compositae) on CCl4 induced
11. Hepatic damage in rats. Iraqi J Pharm Sci 2008; 17 (1):16-24.
12. Silversteine R M and Webster F X; Spectrometric identification of organic compounds (6th ed.). John Wiley and Sons Inc. USA, 1998.
13. Anonymous, The wealth of India, Raw Materials, vol. 3. CSIR, New Delhi, 1952,127.
14. R.N.Yadav, Sujeet Kumar Singh. Asian journal of Chemistry, 2004;16(3-4): 1978-1980.
15. Patel Amish J, Pharmacognostical, Phytochemical and Pharmacological investigation of Echinops echinatusRoxb.
16. Sumia Fatima, Sameera Afroz, Abdul Saheel Qureshi,
17. Antidiabetic activity of hydroalcoholic root extract of Echinops echinatus and its beneficial effects on Neuropathy in experimental rats. Indian journal of Research in pharmacy and biotechnology 2017; 5(1): 19- 27.
18. Rudrappa JN,Mohmoud R. Free radical scavenging Activity of Echinops echinatus Roxb root. Iranian Journal of Pharmacolgy and Therapeutics 2010; 9(2):0-0
19. Ali, M. Y., et al. (2015). “Phytochemical and pharmacological potential of Echinopus echinatus.” Journal of Ethnopharmacology, 164, 291-299.
20. Nascimento, A. C., et al. (2018). “Evaluation of the anti-inflammatory and analgesic effects of Echinopus echinatus.” Phytotherapy Research, 32(10), 1984-1991.
21. Ferreira, I. C. F. R., et al. (2016). “Antioxidant and antimicrobial activities of Echinopus echinatus extracts.” Food Chemistry, 211, 566-573
22. Sharma, S., et al. (2017). “Phytochemical analysis and antioxidant activity of Echinopus echinatus.” Asian Pacific Journal of Tropical Medicine, 10(8), 778-785.
23. Calixto, J. B., et al. (2008). “Phytochemical constituents of Echinopus echinatus and their biological activities.” Brazilian Journal of Pharmacognosy, 18(4), 598-604.
24. Gonçalves, F. M., et al. (2019). “Chemical composition and biological activity of Echinopus echinatus extracts.” Natural Product Research, 33(23), 3423-3429.
25. Akinmoladun, J. O., et al. (2020). “Phytochemical screening and antimicrobial activity of Echinopus echinatus.” Journal of Applied Pharmaceutical Science, 10(2), 65-71.
26. Moghadamtousi, S. Z., et al. (2014). “Phytochemical analysis and biological activities of Echinopus echinatus.” BMC Complementary and Alternative Medicine, 14, 206.
27. Kumar, A., et al. (2018). “Phytochemical profiling of Echinopus echinatus and its potential health benefits.” Journal of Medicinal Plants Research, 12(6), 103-110
28. Zhang, Y., et al. (2020). “Phytochemical constituents of Echinopus echinatus and their pharmacological properties.” Natural Product Communications, 15(2), 1-6.
29. Ferreira, I. C. F. R., et al. (2016). “Chemical composition and bioactivity of Echinopus echinatus extracts.” Food Chemistry, 211, 573-580.
30. Choudhary, M. I., et al. (2019). “Morphological characteristics and distribution of Echinopus echinatus.” Phytochemistry Reviews, 18(1), 129-143.
31. Agrawal M, Nahata A, Dixit VK. Protective effects of Echinops echinatus on testosterone-induced prostatic Hyperplasia in rats. Europian Journal of Integrative Medicine 2012; 4(2):177-85.
32. Padashetty SA, Mishra SH. Effect of terpenoidal Fraction of Echinops echinatus roots on reproductive Parameters of male rats. J Nat Med 2007; 61:452-57.