Volume : 12, Issue : 08, August- 2025
Title:
DESIGN, SYNTHESIS, AND CHARACTERIZATION OF SALMETEROL-LOADED POLYMERIC NANOPARTICLES
Authors :
Ch. S. Vijayavani *, V.Kalyan varma , M.L.N.harshitha, S.Sai Sahasra, V.Harika , A. Anusha
Abstract :
Nanoparticles are formulated to target the drug to the specific organ site and to control the rate of delivery of drug. By encapsulating a drug into nanostructures, the being of the drug in the systemic circulation can be prolonged and thus improve perforation into the target tissue and decrease the toxicity. The main aim of this study is to achieve prolonged release of Salmeterol such that the dosing frequency of the drug can be reduced, by which we may decrease the side effects and improve patient compliance. By formulating Salmeterol as nanoparticles, we can directly deliver the drug to the asthma. Investigation of the preparation, characterization, and in-vitro delivery of the nanoparticles was carried out. The different formulations of with different concentrations of drug-polymer and surfactant were examined and finalized. which can accomplish belongings in drug encapsulation and drug delivery kinetics of the nanoparticles.
Keywords: Salmeterol, polymer, solvent evaporation method, in vitro drug release studies, Zero order kinetics.
Cite This Article:
Please cite this article in press CH. S. Vijayavani et al., Design, Synthesis, And Characterization Of Salmeterol-Loaded Polymeric Nanoparticles., Indo Am. J. P. Sci, 2025; 12(08).
Number of Downloads : 10
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