Volume : 12, Issue : 08, August- 2025
Title:
FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLET OF METOCLOPRAMIDE
Authors :
V. Archana*, K.Amogha, K.Anitha, K.Siddu, K.Shireesha, P.Venugopal
Abstract :
The objective of the study was to formulate and evaluate Mouth Dissolving Tablets Of Metoclopramide . Direct compression method was used to formulate mouth dissolving tablet of Metoclopramide by employing different super disintegrants and magnesium stearate (lubricant), Talc. These prepared formulations were then evaluated. Dissolution and drug content tests were performed using USP apparatus II and ultraviolet spectrophotometry, respectively. All formulations showed compliance with pharmacopeia standards. The effect of super disintegrates concentration and direct compression method on drug release profile was studied. Release profile of F4 were found to be satisfactory comparing to other formulations. F4 Formulation as processed excipient was found to be the best super disintegrants for the preparation of Metoclopramide mouth dissolving tablets formulations. Due to it has exhibited faster disintegration time and best dissolution profile when compared to other formulations.
Keywords: Metoclopramide, super disintegrates, FTIR Studies, direct compression technique, in-vitro drug release studies.
Cite This Article:
Please cite this article in press V.Archana et al., Formulation And Evaluation Of Mouth Dissolving Tablet Of Metoclopramide., Indo Am. J. P. Sci, 2025; 12(08).
Number of Downloads : 10
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