Volume : 12, Issue : 02, February – 2025
Title:
SYNTHESIS, CHARACTERIZATION AND INVITRO EVALUATION OF 4,6-DIPHENYL PYRIMIDINE-2(1H)- THIONE DERIVATIVES.
Authors :
K. Durga Lalitha Rani, A. Teja, V. Mythili, V. Naveen Kumar, D. Kiranmayee, Sudha Rani. K*.
Abstract :
A Series of Bioactive compounds , 4,6-diphenyl Pyrimidine-2(1H)-thione(1a), 4-(4-chlorophenyl)-6-phenylpyrimidine-2-(1H)-thione(1b),4-(4-aminophenyl)-6-phenyl pyrimidine -2(1H) thione (2a) , 4-(4-nitro phenyl)-6-phenyl pyrimidine-2(1H)- thione (2b) , 4-(4- methoxy phenyl)-6-phenyl pyrimidne-2(1H)-thione(3a), were synthesized according to the literature methods . The synthesized compounds were characterized by NMR, IR & Mass spectroscopy. All the compounds have been evaluated for invitro anti-bacterial activity, anti-
fungal activity, anti-helmintic activity and were compared with their corresponding standards.
Keywords: 4,6-diphenyl pyrimidine-2(1H)-Thione, Chalcones, Aldehydes, Thiourea,Ciprofloxaci Fluconazole,Albendazole.
Cite This Article:
Please cite this article in press K. Sudharani et al., Synthesis, Characterization And Invitro Evaluation Of 4,6-Diphenyl Pyrimidine-2(1h)- Thione Derivatives., Indo Am. J. P. Sci, 2025; 12 (02).
Number of Downloads : 10
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