Volume : 12, Issue : 06, June – 2025
Title:
EVALUATION OF THE ANTI-DIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF CORCHOROS IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Authors :
Y Sridhar*, G Vijaya Kumar, Koilakonda Ramya
Abstract :
The present study investigates the anti-diabetic and antioxidant potential of the ethanolic extract of Corchorus species in streptozotocin (STZ) induced diabetic rats. The extract was evaluated for its efficacy in modulating blood glucose levels and improving oxidative stress biomarkers. In vitro antioxidant activity was assessed through various free radical scavenging assays, including superoxide radical, nitric oxide, hydrogen peroxide, hydroxyl radical, and DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assays. The extract demonstrated significant free radical scavenging activity across all models, indicating strong antioxidant potential. In vivo, the ethanolic extract showed a protective effect against STZ-induced hyperglycemia and oxidative damage in diabetic rats. These findings suggest that the ethanolic extract of Corchorus possesses promising anti-diabetic and antioxidant activities and may serve as a potential natural therapeutic agent for the management of diabetes mellitus.
Keywords: Corchorus, Anti-diabetic activity, Streptozotocin-induced diabetes, Antioxidant activity.
Cite This Article:
Please cite this article in press Y Sridhar et al Evaluation Of The Anti-Diabetic Activity Of Ethanolic Extract Of Corchoros In Streptozotocin Induced Diabetic Rats.., Indo Am. J. P. Sci, 2025; 12(07).
Number of Downloads : 10
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