Volume : 12, Issue : 06, June – 2025
Title:
STUDYING THE CONTROLLED RELEASE EFFECT OF VARIOUS POLYMER CARRIER ON DRUG RELEASE
Authors :
Mohammed Sameer Qureshi , Gurrapu Nikhita, Syed Romaanuddin,Bandoni Nikhil , Sushma Desai *
Abstract :
Purpose: The present study was undertaken to understand the polymer-controlled release effect on the drug and evaluation studies of its final product formation. Oral Solid dosage forms prepared using six polymers Eudragit grades RL 100 & L100, HPMC grades 15LV and E15LV, Carbopol and Gum Karaya.
Methodology: Wet granulation method was used to prepare the oral solid dosage forms using Paracetamol as model drug. The prepared oral solid dosage forms
Results & discussion: The physical parameters of post compression evaluation studies and drug release studies were found to be compliant with the I.P standards. The optimized polymer carrier was found to be gum karaya with good controlled release with 88 % at the end 2 hr of drug release studies.
Conclusion: with the obtained results of evaluation it can be concluded that polymer carriers Gum Karaya has shown better post compression parameters and controlled release behavior by dissolution studies fulfilling the current study objective.
Keywords: Polymer Carrier, Paracetamol, Controlled Release.
Cite This Article:
Please cite this article in press Sushma Desai et al., Studying The Controlled Release Effect Of Various Polymer Carrier On Drug Release.., Indo Am. J. P. Sci, 2025; 12(07).
Number of Downloads : 10
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