Volume : 12, Issue : 06, June – 2025
Title:
FORMULATION AND EVALUATION OF BUPRENORPHINE BUCCAL TABLETS
Authors :
CH.Kantlam, G. Renuka*, Shivaleela Suguru, Syeda Sadaf Makki, Thalari Sahish, Varre Shirisha Reddy, Yanabothula Komalika
Abstract :
Buccal tablet of oral formulations of these drugs have been developed to improve their acceptability to patients and thus improve compliance. The focus of present investigation was to improve solubility, bioavailability and to achieved rapid onset action. Buccal tablets of Buprenorphine were prepared by direct compression technique. Four Formulations were formulated using Ethyl cellulose and Carboxy methyl cellulose sodium as polymers on Swelling index, Disintegration time. In addition, the prepared tablets were also evaluated for weight variation, thickness, moisture absorption, friability, content uniformity, wetting time and drug release studies. Formulation reveals fast dissolution and disintegration rate of optimized Buprenorphine buccal tablets.
Key words: Buprenorphine, Direct compression technique, FTIR studies, Synthetic polymer, Drug release studies.
Cite This Article:
Please cite this article in press Ch. Kantlam et al., Formulation And Evaluation Of Buprenorphine Buccal Tablets., Indo Am. J. P. Sci, 2025; 12(07).
Number of Downloads : 10
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