Volume : 12, Issue : 06, June – 2025

Title:

ANALYZING THE SHORT AND MID-TERM RESULTS IN HIRSCHSPRUNG’S DISEASE IN CHILDREN UNDERGOING VARIOUS TREATMENTS

Authors :

Usama Ali Malik, Fiza Malik, Abdul Hadi Khan, Hassan Ilyas, Sidra Arshad, Muhammad Fahad Khaliq

Abstract :

Background: Hirschsprung disease (HD) is a congenital disease characterized by the absence of ganglion cells in parts of the bowel, resulting in functional obstruction. Outcomes highly depend on early diagnosis and surgical treatment, which, in turn, depend on early identification of findings. However, short- and mid-term postoperative outcomes vary depending on the surgical technique employed.
Objective: This study aims to evaluate the short- and mid-term outcomes in children with Hirschsprung disease (HD) who underwent different surgical procedures.
Methods: This retrospective observational study was conducted at Services Hospital between June 2022 and May 2023. Fifty pediatric patients with Hirschsprung disease who underwent various surgical procedures were included. Short-term complications (within 3 months postoperatively) and mid-term outcomes (up to 6 months postoperatively) were evaluated by assessing bowel function, incidence of enterocolitis, and growth parameters. Data were collected through medical records and patient follow-up.
Results: Among the 50 patients, 10 (20%) underwent laparoscopic-assisted transanal endorectal pull-through, 12 (24%) had Swenson, 10 (20%) had the Duhamel procedure, and 18 (36%) received the Soave procedure. Short-term complications included perianal excoriation (32%), postoperative enterocolitis (24%), and anastomotic leak (6%). At mid-term follow-up, 76% of patients demonstrated satisfactory bowel function, 18% experienced occasional constipation, and 6% had recurrent enterocolitis. Patients who underwent transanal endorectal pull-through generally showed better continence and growth recovery compared to those who underwent other procedures.”
Conclusion: This study concluded that the choice of surgical procedure significantly influenced both short- and mid-term outcomes in children with Hirschsprung disease. Laparoscopic-assisted associated with better bowel function, fewer complications, and an overall improved quality of life, making it the preferred approach in most cases.
Keywords: Hirschsprung’s disease, pediatric surgery, Transanal endorectal pull-through, short-term outcomes, mid-term outcomes, surgical treatment.

Cite This Article:

Please cite this article in press Usama Ali Malik et al., Analyzing The Short And Mid-Term Results In Hirschsprung’s Disease In Children Undergoing Various Treatments., Indo Am. J. P. Sci, 2025; 12(07).

Number of Downloads : 10

References:

1. Cheng T, Zhang Z, Zhou R, Liu W, Xiao P, Wu L, Ma Y, Niu W, Chen Y, Li B, Pierro A. Clinical Characteristics and Postoperative Functional Outcomes in Children With Mowat-Wilson Syndrome and Hirschsprung’s Disease: A Single-center Study. Journal of Pediatric Surgery. 2025 Apr 1;60(4):162217.
2. Hosseinpour M, Mostafavi M, Ahmadi B, Davari HA, Nazem M. Evaluation Of Short And Mid-Term Outcomes In Children With Hirschsprung’s Disease Undergoing Different Surgical Procedures. Iranian Journal of Pediatric Surgery Vol. 2022;8(2).
3. Oltean I, Hayawi L, Larocca V, Bijelić V, Beveridge E, Kaur M, Grandpierre V, Kanyinda J, Nasr A. Quality of life outcomes in children after surgery for Hirschsprung disease and anorectal malformations: a systematic review and meta-analysis. World Journal of Pediatric Surgery. 2022 Nov 10;5(4):e000447.
4. Zhang Y, Xiang X, Li X, Feng W, Guo Z. Early intervention in Hirschsprung’s disease: effects on enterocolitis and surgical outcomes. BMC pediatrics. 2024 Jul 26;24(1):476.
5. Cheng T, Zhang Z, Zhou R, Liu W, Xiao P, Wu L, Ma Y, Niu W, Chen Y, Li B, Pierro A. Clinical Characteristics and Postoperative Functional Outcomes in Children With Mowat-Wilson Syndrome and Hirschsprung’s Disease: A Single-center Study. Journal of Pediatric Surgery. 2025 Apr 1;60(4):162217.
6. Rossi D, Granström AL, Teunissen NM, Wijnen R, Wester T, Sloots C. Bridging the Gap: Reporting Baseline Characteristics, Process and Outcome Parameters in Hirschsprung’s Disease. A Systematic Review. European Journal of Pediatric Surgery: Official Journal of Austrian Association of Pediatric Surgery…[et al]= Zeitschrift fur Kinderchirurgie. 2023 Oct 26.
7. Trovalusci E, Thelele T, Midrio P, Bebington C, Westgarth-Taylor C, Brisighelli G. The burden of delayed diagnosis in Hirschsprung disease: insights from a Paediatric Colorectal Centre in South Africa. BMC pediatrics. 2025 Jul 10;25(1):547.
8. Saleem M, Butt J, Shaukat Z, Hashim I, Moeezah, Majeed F, Kamran M, Saleem U. Functional outcome of Hirschsprung’s disease in children: A single center study at The Children’s Hospital Lahore. Pediatric surgery international. 2023 Apr 11;39(1):176.
9. Saleem M, Butt J, Shoukat Z, Hashim I, Muhammad M, Majeed F, Saleem U, Kamran M. Functional Outcomes of Hirschsprung’s Disease in Children-A Single Center Study Done at The Children’s Hospital Lahore.
10. Kim SH, Cho YH, Kim HY. Assessment of defecation function beyond infantile period for transanal single-stage endorectal pull-through in Hirschsprung disease. Annals of surgical treatment and research. 2021 Oct 1;101(4):231-9.
11. Li W, Lin M, Hu H, Sun Q, Su C, Wang C, Li Y, Li Y, Chen J, Luo Y. Surgical management of Hirschsprung’s disease: A comparative study between conventional laparoscopic surgery, transumbilical single-site laparoscopic surgery, and robotic surgery. Frontiers in surgery. 2022 Jul 4;9:924850.
12. Nazem M, Hosseinpour M, Riahinezhad M, Rafie MH, Nassiri GM. Comparison of the Results of Ultrasound-Guided Using Surface Probe and Non-Ultrasound-Guided Botulinum Toxin Injection into the Internal Anal Sphincter in Children with Constipation—Randomized Clinical Trial. Advanced Biomedical Research. 2025 May 1;14(1):42.
13. Hou J, Feng W, Zhao H, Cui M, Wang Y, Guo Z, Liu W. Robotic-assisted Swenson procedure for Hirschsprung’s disease with a median age of 35 days: a single-center retrospective study. Pediatric Surgery International. 2025 Dec;41(1):1-9.
14. Fakhry T, Rabee A, Lolah M, Nabil A. Laparoscopic-assisted versus complete transanal pull-through using the Swenson technique in treatment of Hirschsprung’s disease. Annals of Pediatric Surgery. 2023 Jul 17;19(1).
15. Shankar G, Umashankar VB, Jadhav V, Munianjanappa N. Modified Duhamel pull-through vs. Trans-anal endorectal pull-through in children with Hirschsprung’s disease: Outcome comparison from a single center over 14 years.