Volume : 12, Issue : 03, March – 2025

Title:

OVERVIEW OF TRANSDERMAL DRUG DELIVERY SYSTEM IN TRANSDERMAL PATCHES

Authors :

Radhesham A. Tekale*, Shrihari V Nighot, Vaishnavi V Tawde, Swati P. Deshmukh

Abstract :

Oral route is the most popular route of drug delivery system but it has some disadvantages including first pass metabolism, drug degradation etc in gastrointestinal tract due to enzymes,pl etc. To overenme these problems, a novel drug delivery system was developed by Chien in1992, Banker in 1990, Guy in 1996. It was Transdermal patches or Transdermal delivery system. In this Types of Transdermal Drug Delivery System Single-layer Drug-in-Adhesive System: In this type of patch the adhesive layer of this system contains the drug. The adhesive layer not only serves to adhere the various layers together, along with the entire system to the skin, but it is also responsible for system medicated adhesive patches are prepared which deliver the re-releasing the drug.
Fentanyl, lidocaine and testosterone; combination patches containing more than one drug forcontraception and hormone replacement, and iontophoretic and ultrasonic delivery systems for analgesia. Between 1979 and 2002, a new patch was approved on average every 2.2 years. Over the past 5 years(2003-2007), that rate has more than tripled to a new transdermal delivery system every 7.5 months. It is estimated that more than one billion transdermal patches are currently manufactured each year.[2]
Keywords: Transdermal drug delivery system (TDDS) Transdermal patches Controlled drug release Skin permeation Permeation enhancers Polymer matrix Drug reservoir system Adhesive layer

Cite This Article:

Please cite this article in press Radhesham A. Tekale et al., Overview Of Transdermal Drug Delivery System In Transdermal Patches., Indo Am. J. P. Sci, 2025; 12(05).

Number of Downloads : 10

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