Volume : 12, Issue : 11, November – 2025

Title:

SCREENING OF INCISION WOUND MODEL USING ALCOHOLIC EXTRACT OF VARIOUS SPECIES OF HIBISCUS FLOWERS IN ALBINO WISTAR RATS

Authors :

Amena Banu*, Varunkumar, Arshiya Naaz, Bhimabai.D, Sonali Vilas Badganchi and Nikita Sanjeev

Abstract :

The present study aimed to evaluate the wound healing potential of Hibiscus plant extracts using the incision wound model in albino rats. Wound healing is a complex biological process involving inflammation, tissue formation, and remodeling. Traditional medicine has long used Hibiscus species, particularly Hibiscus rosa-sinensis, for treating wounds due to their antioxidant, anti-inflammatory, and antimicrobial properties.
In this study, animals were divided into three groups: control (base ointment), standard (povidone-iodine), and test (5% and 10% Hibiscus extract ointment). A standardized 6 cm incision wound was made on the dorsal surface of anesthetized rats, and treatments were applied topically once daily for 10 days. Wound healing was assessed through tensile strength measurements, histopathological analysis, and observational parameters such as wound contraction and epithelialization.
The results demonstrated that animals treated with Hibiscus extract showed significantly increased tensile strength compared to the control group (p < 0.05), along with improved collagen formation and faster re-epithelialization. Histological studies confirmed enhanced fibroblast proliferation and organized tissue regeneration.
These findings indicate that Hibiscus plant extract possesses significant wound healing activity, supporting its traditional use and potential as a natural therapeutic agent in wound management.

Cite This Article:

Please cite this article in press Amena Banu et al., Screening Of Incision Wound Model Using Alcoholic Extract Of Various Species Of Hibiscus Flowers In Albino Wistar Rats, Indo Am. J. P. Sci, 2025; 12(11).

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