Volume : 12, Issue : 11, November – 2025
Title:
EVALUATION OF ANTI-MICROBIAL PROPERTY OF VINCA ROSEUS PLANT EXTRACT
Authors :
Umesh Mitte*, Praveen Singh, Sree Kanth, Shilpa, Sakshi Bhandari and Sangharakshit
Abstract :
Ayurveda, the traditional system of Indian medicine, emphasizes the therapeutic potential of plants. Catharanthus roseus (L.) commonly known as periwinkle is a significant medicinal plant recognized for its w ide range of pharmacological activities, including anti-tumour, anti- diabetic, anti-microbial, antioxidant, and anti-mutagenic properties. Native to Madagascar, this evergreen plant contains over 130 alkaloids, such as ajmalicine, vincristine, vinblastine, reserpine, and Rauba sine, which are clinically important for treating various cancers including Hodgkin’s disease, breast cancer, skin cancer, and lymphoblastic leukaemia. Owing to its endangered status, conservation through micro propagation techniques is essential.
In the present study, leaf extracts of Catharanthus roseus were prepared using acetone, ethanol, and chloroform to evaluate their antimicrobial potential against selected pathogenic microorganisms through the agar well diffusion method. Among the tested solvents, ethanolic extracts showed the highest antibacterial activity. Streptococcus species exhibited maximum susceptibility, followed by Escherichia coli. The findings indicate that Catharanthus roseus possesses promising antimicrobial activity and can be utilized as a potential source for developing novel herbal formulations. Further studies are recommended to explore its synergistic effects when combined with other medicinal plants.
Key Words: Catharanthus roseus, Diffusion method, Antimicrobial potential
Cite This Article:
Please cite this article in press Umesh Mitte et al., Evaluation of anti-microbial property of Vinca roseus plant extract, Indo Am. J. P. Sci, 2025; 12(11).
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