Volume : 12, Issue : 11, November – 2025
Title:
FORMULATION AND EVALUTION OF LIQUORICE BODY WASH
Authors :
Subodh Subhash Navgire*, Pranay Ramesh Pawar, Mr. Akash Nimbone, Dr. Kavita Kulkarni
Abstract :
The present study aimed to formulate and evaluate a herbal liquorice-based body wash enriched with multiple botanicals possessing antioxidant, anti-inflammatory, antimicrobial, and skin-rejuvenating properties. Liquorice extract was selected as the primary active ingredient due to its proven skin-soothing, depigmenting, and anti-inflammatory effects, complemented by aloe vera, tulsi, neem, eucalyptus oil, almond oil, glycerine, rose essence, and multani mitti. The formulation was prepared by sequentially blending the extract–oil phase with a mild Castile soap base, followed by incorporation of the aqueous phase and aromatic agents. The final product was evaluated for organoleptic properties, homogeneity, pH, viscosity, spreadability, washability, and skin irritation potential.
The formulated body wash exhibited an aesthetically acceptable pinkish-brown color, pleasant odor, and smooth consistency with good homogeneity. The pH (7.2) was within the desirable range for topical cleansing formulations, ensuring compatibility with the skin. Spreadability and washability results confirmed ease of application and removal, while viscosity measurements (29,970 cps at 20 rpm) indicated optimal thickness and flow characteristics essential for consumer acceptability. No signs of redness, irritation, or discomfort were observed during skin irritation studies, demonstrating the safety of the formulation. Overall, the herbal liquorice body wash showed excellent stability, favorable physicochemical characteristics, and beneficial cleansing properties, making it a promising natural alternative for daily skincare and potential use in conditions associated with inflammation or dryness.
KEYWORDS: Liquorice extract; Herbal body wash; Glycyrrhiza glabra; Cosmetic formulation; Skin care; Aloe vera; Tulsi extract; Multani mitti; Eucalyptus oil; Physicochemical evaluation; Topical herbal product; Natural cleanser.
Cite This Article:
Please cite this article in press Subodh Subhash Navgire et al., Formulation And Evalution Of Liquorice Body Wash, Indo Am. J. P. Sci, 2025; 12(11).
REFERENCES:
1. Sarac G, Koca TT, Baglan T. A brief summary of clinical types of psoriasis. North Clin Istanb. 2016;3(1):79–82. doi:10.14744/nci.2016.16023.
2. Urban K, Chu S, Giesey RL, Mehrmal S, Uppal P, Delost ME. Burden of skin disease and socioeconomic status in Asia: analysis from the Global Burden of Disease Study 1990–2017. JAAD Int. 2021;2:40–50. doi:10.1016/j.jdin.2020.10.006.
3. Danielsen K, Olsen AO, Wilsgaard T, Furberg AS. Is the prevalence of psoriasis increasing? A 30-year follow-up. Br J Dermatol. 2013;168(6):1303–10. doi:10.1111/bjd.12230.
4. Harden JL, Krueger JG, Bowcock AM. The immunogenetics of psoriasis: a comprehensive review. J Autoimmun. 2015;64:66–73. doi:10.1016/j.jaut.2015.07.008.
5. Kim WB, Jerome D, Yeung J. Diagnosis and management of psoriasis. Can Fam Physician. 2017;63(4):278–85.
6. Merola JF, Tian H, Patil D, Richardson C, Scott A, Chen YH. Incidence and prevalence of psoriatic arthritis stratified by psoriasis disease severity. J Am Acad Dermatol. 2022;86(4):748–57. doi:10.1016/j.jaad.2021.09.019.
7. Chalmers R, O’Sullivan T, Owen CM, Griffiths CE. Interventions for guttate psoriasis. Cochrane Database Syst Rev. 2019;4:CD001213. doi:10.1002/14651858.CD001213.pub2.
8. Micali G, Verzi AE, Giuffrida G, Panebianco E, Musumeci ML, Lacarrubba F. Inverse psoriasis: diagnosis and treatment options. Clin Cosmet Investig Dermatol. 2019;12:953–9. doi:10.2147/CCID.S189000.
9. Benjegerdes KE, Hyde K, Kivelevitch D, Mansouri B. Pustular psoriasis: pathophysiology and current treatment. Psoriasis (Auckl). 2016;6:131–44. doi:10.2147/PTT.S98954.
10. Singh RK, Lee KM, Ucmak D, Brodsky M, Atanelov Z, Farahnik B. Erythrodermic psoriasis: current perspectives. Psoriasis (Auckl). 2016;6:93–104. doi:10.2147/PTT.S101232.
11. Sato Y, Ogawa E, Okuyama R. Role of innate immune cells in psoriasis. Int J Mol Sci. 2020;21(18):6604. doi:10.3390/ijms21186604.
12. Mosca M, Hong J, Hadeler E, Brownstone N, Bhutani T, Liao W. Scalp psoriasis: a review and management update. Dermatol Ther (Heidelb). 2021;11(3):769–97. doi:10.1007/s13555-021-00521-z.
13. Bahadur S, Sharma M. Liposome-based drug delivery for psoriasis: a comprehensive review. Curr Pharm Biotechnol. 2023;24(11):1383–96. doi:10.2174/1389201024666221213144228.
14. Rendon A, Schakel K. Psoriasis pathogenesis and treatment. Int J Mol Sci. 2019;20(6):1475. doi:10.3390/ijms20061475.
15. Wahab S, Annadurai S, Abullais SS, Das G, Ahmad W, Ahmad MF. Glycyrrhiza glabra (licorice): phytochemistry, biological activities, clinical evidence and toxicology. Plants. 2021;10(12):2751. doi:10.3390/plants10122751.
16. Tiwari A, Tiwari A. Comparative study of polyphenolic content in Acacia catechu bark extracts. Asian J Pharm Clin Res. 2024;17(6):45–50. doi:10.22159/ajpcr.2024.v17i6.50809.
17. Chhabra R, Sharma R, Kaur A, Sharma VK, Thakur S. Phytochemical characterization and antifungal ability of Meliaceae species. Agric Res J. 2023;60(1):146–52. doi:10.5958/2395-146X.2023.00023.6.
18. Fiore C, Eisenhut M, Ragazzi E, Zanchin G, Armanini D. History of therapeutic use of liquorice in Europe. J Ethnopharmacol. 2005;99(3):317–24. doi:10.1016/j.jep.2005.04.015.
19. Pastorino G, Cornara L, Soares S, Rodrigues F, Oliveira MB. Liquorice: phytochemical and pharmacological review. Phytother Res. 2018;32(12):2323–39. doi:10.1002/ptr.6178.
20. Gaur R, Yadav KS, Verma RK, Yadav NP, Bhakuni RS. In vivo antidiabetic activity of isoliquiritigenin and liquiritigenin derivatives. Phytomedicine. 2014;21(4):415–22. doi:10.1016/j.phymed.2013.10.015.
21. Rizzato G, Scalabrin E, Radaelli M, Capodaglio G, Piccolo O. Exploration of the licorice metabolome. Food Chem. 2017;221:959–68. doi:10.1016/j.foodchem.2016.11.068.
22. Cerulli A, Masullo M, Montoro P, Piacente S. Licorice (G. glabra, G. uralensis, G. inflata) and cosmeceutical uses. Cosmetics. 2022;9(1):7. doi:10.3390/cosmetics9010007.
23. Desai J, Patel RJ, Desai D. Karanjin-loaded emulgel for psoriasis. Indian J Pharm Educ Res. 2023;57(2):393–400. doi:10.5530/ijper.57.2.49.
24. Malavi S, Kumbhar P, Manjappa A, Disouza J, Dwivedi J. Emulgel for improved topical delivery of tretinoin. Ann Pharm Fr. 2022;80(2):157–68. doi:10.1016/j.pharma.2021.05.004.
25. Sharma A, Singh AP, Harikumar SL. Nanoemulsion-based gel for nitrendipine delivery. Drug Dev Ind Pharm. 2020;46(2):329–42. doi:10.1080/03639045.2020.1721527.
26. He E, Li H, Li X, Wu X, Lei K, Diao Y. Indirubin-loaded microemulsion gel: anti-psoriatic activity. Int J Mol Sci. 2022;23(7):3798. doi:10.3390/ijms23073798.
27. Yadav R, Pandey NK, Kukkar R. Emulgel with silver nanoparticles and vitamin D3 for wound healing. Int J Appl Pharm. 2024;16(3):149–58. doi:10.22159/ijap.2024v16i3.50344.
28. Bhardwaj S, Gaur PK, Tiwari A. Topical nanoemulgel for psoriasis: combined therapy approach. Assay Drug Dev Technol. 2022;20(1):42–54. doi:10.1089/adt.2021.112.
29. Cao J, Jiang M, Hua S, Yang L, Li P. Gas chromatography and GC–MS in quality control of Chinese medicines. In: Springer; 2024. p.451–74. doi:10.1007/978-981-99-9871-5_14.
30. Sarikurkcu C, Ozer MS, Cakir A, Eskici M, Mete E. GC/MS evaluation and antioxidant activity of Phlomis bourgaei. Evid Based Complement Alternat Med. 2013;2013:293080. doi:10.1155/2013/293080.
31. Mittal S, Ali J, Baboota S. Enhanced anti-psoriatic activity of tacrolimus nanoemulsion gel using omega-3 fatty acid oils. J Drug Deliv Sci Technol. 2021;63:102458. doi:10.1016/j.jddst.2021.102458.