Volume : 12, Issue : 11, November – 2025
Title:
DEVELOPMENT AND ASSESSMENT OF CONTROLLED-RELEASE TABLETS OF VERAPAMIL USING NATURAL POLYMERS
Authors :
Mubashir Ahmed Khan, Alisha Ishrath*, Dr. Sayeed Arif Ullah Hussain, Dr. Faizan Sayeed and Dr. Abdul Sayeed
Abstract :
Based on the experimental findings presented above, it can be concluded that Verapamil Controlled-Release Tablets formulated with natural polymers yielded satisfactory outcomes concerning various micromeritic properties, dissolution rates, and drug content. The Controlled-Release Tablets developed exhibited acceptable results for several physicochemical parameters, including weight variation. The Verapamil Controlled-Release Tablets demonstrate a controlled release profile. Among all the verapamil formulations, F5 was chosen due to its drug release characteristics within a specified timeframe. In-vitro release rate assessments indicated that F5 was optimized for minimal drug release. The stability of the F5 formulation was confirmed at 40°C and 75% relative humidity over a duration of three months. FT-IR analyses indicated that there was no interaction between verapamil and the polymers.
Keywords: Controlled release tablets, Verapamil, HPMC, ethyl cellulose, xanthan gum
Cite This Article:
Please cite this article in press Alisha Ishrath et al., Development And Assessment Of Controlled-Release Tablets Of Verapamil Using Natural Polymers, Indo Am. J. P. Sci, 2025; 12(11).
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