Volume : 12, Issue : 11, November – 2025
Title:
NOVEL FAST DISINTEGRATING TABLET OF BISOPROLOL FUMARATE WITH ITS DEVELOPMENT AND CHARACTERIZATION FOR PATIENT COMPLIANCES
Authors :
Miss. Ankita Suresh Jaiswal,Mr. Amol G. Jadhao, Dr. Ashutosh Kumar Dash
Abstract :
Bisoprolol Fumarate (BF), a selective β1-adrenergic receptor blocker, is widely prescribed for hypertension and chronic heart diseases. However, conventional tablets often pose swallowing difficulties for geriatric, pediatric, and dysphagic patients, leading to poor adherence. Fast Disintegrating Tablets (FDTs) have emerged as a promising patient-centric dosage form that dissolves rapidly in the oral cavity without the need for water, ensuring quicker onset of action and improved compliance. This review summarizes the formulation strategies, excipient selection, and manufacturing approaches involved in developing Bisoprolol Fumarate FDTs. Emphasis is placed on the role of superdisintegrants, taste-masking methods, and critical evaluation parameters such as disintegration time, wetting time, hardness, and dissolution performance. Recent advancements, challenges, and future perspectives in optimizing FDTs for cardiovascular therapy are also discussed. Overall, Bisoprolol Fumarate FDTs represent an efficient and patient-friendly alternative that enhances therapeutic outcomes and dosage convenience.
Cite This Article:
Please cite this article in press Ankita Suresh Jaiswal et al., Novel Fast Disintegrating Tablet Of Bisoprolol Fumarate With Its Development And Characterization For Patient Compliances, Indo Am. J. P. Sci, 2025; 12(11).
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