Volume : 12, Issue : 11, November – 2025

Title:

REVIEW ON SUSTAINED RELEASE DOSAGE FORMS IN THE MANAGEMENT OF PEPTIC ULCER DISEASE

Authors :

Pooja D. Jadhav, Priya M. Dandekar, Dr. Ashutosh Kumar Dash

Abstract :

Peptic Ulcer Disease (PUD) is a common gastrointestinal problem caused by an imbalance between gastric acid secretion and mucosal protection. Conventional anti-ulcer drugs provide quick relief but require frequent dosing and may produce side effects. To overcome these issues, Sustained Release (SR) dosage forms are developed to maintain a steady drug level for a longer period, reduce dosing frequency, and improve patient compliance. Herbal medicines are gaining attention due to their safety and strong gastroprotective properties. Among them, Emblica officinalis (EO), commonly known as Amla, contains vitamin C, tannins, and flavonoids that show anti-ulcer, antioxidant, and mucosal-healing activity. This review highlights the role of EO in anti-ulcer therapy, its phytochemical profile, mechanisms of action, and its suitability for SR formulations. The paper also discusses formulation techniques, evaluation parameters, and previous research supporting the development of an effective herbal-based SR anti-ulcer dosage form.
Keywords: Peptic Ulcer Disease (PUD); Sustained Release (SR) Formulation; Emblica officinalis (Amla); Anti-ulcer Activity; Herbal Medicine; Gastroprotective Agents; Phytochemicals.

Cite This Article:

Please cite this article in press Pooja D. Jadhav et al., Review On Sustained Release Dosage Forms In The Management Of Peptic Ulcer Disease, Indo Am. J. P. Sci, 2025; 12(11).

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