Volume : 12, Issue : 10, October – 2025

Title:

EXPLORATORY STUDY ON THE ROLE OF INHALED CORTICOSTEROIDS IN ASTHMA MANAGEMENT

Authors :

Gayatri Kailas Bhale , Amruta G Bawane, Dr.S.P.Deshmukh

Abstract :

Asthma is a chronic, heterogeneous respiratory disorder characterized by persistent airway inflammation, hyperresponsiveness, and structural remodeling, resulting in recurrent episodes of wheezing, dyspnea, chest tightness, and coughing. The etiology of asthma involves complex interactions between genetic predisposition, environmental exposures, and immune dysregulation. Accurate diagnosis requires comprehensive clinical evaluation supported by lung function tests and assessment of airway inflammation. Asthma management prioritizes inhaled corticosteroids (ICS) as the cornerstone therapy due to their potent anti-inflammatory effects mediated through glucocorticoid receptor binding and modulation of pro-inflammatory cytokines and immune cells. Common ICS agents—beclomethasone dipropionate, budesonide, and fluticasone propionate—exhibit distinct pharmacological profiles that guide individualized treatment. Effective ICS use improves airway function, reduces exacerbations, and enhances patient quality of life. Optimal outcomes depend on proper inhaler technique, dose titration, and mitigation of local and systemic side effects. Adjunctive therapies including beta-2 agonists, leukotriene receptor antagonists, and biologics complement ICS, particularly in severe or steroid-resistant cases. Comprehensive asthma care also encompasses trigger avoidance, patient education, and regular monitoring. This review underscores the critical role of ICS in asthma management and highlights the importance of personalized, multidisciplinary approaches to achieve sustained disease control and improved long-term respiratory health.

Cite This Article:

Please cite this article in press Gayatri Kailas Bhale et al., Exploratory Study On The Role Of Inhaled Corticosteroids In Asthma Management, Indo Am. J. P. Sci, 2025; 12(10).

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