Volume : 12, Issue : 10, October – 2025

Title:

FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES OF DICLOFENAC SODIUM: A REVIEW

Authors :

Adesh Ramdhan kakade*, Shubham U. Tikait, Dr. Swati P Deshmukh

Abstract :

The development of transdermal patches containing diclofenac sodium has emerged as a promising approach for effective pain management. Diclofenac, a non-steroidal anti-inflammatory drug (NSAID), is commonly used to treat inflammatory conditions, arthritis, and musculoskeletal pain. These include enhanced bioavailability, avoidance of first-pass metabolism, maintenance of steady plasma drug concentrations, non-invasiveness, prolonged therapeutic effects, reduced adverse effects, and improved patient compliance. Transdermal patches are primarily made using NSAIDs (non-steroidal anti-inflammatory medications) to alleviate pain or inflammation. NSAID patches are more convenient and safe to use than the oral dosage type. TDDS provide a convenient, cost-effective, and self-administrable alternative, making them particularly beneficial for drugs that require frequent or long-term dosing. Diclofenac is a well-known nonsteroidal anti-inflammatory drug that is frequently used to treat pain and inflammation symptoms in musculoskeletal conditions, arthritis, toothaches, dysmenorrhea, and other conditions
Keywords: TDDS, Anatomy of Skin , Transdermal Patches, Types, Function, Skin , Method, Evaluation.

Cite This Article:

Please cite this article in press Adesh Ramdhan kakade et al., Formulation And Evaluation Of Transdermal Patches Of Diclofenac Sodium: A Review Indo Am. J. P. Sci, 2025; 12(10).

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