Volume : 13, Issue : 04, April – 2026
Title:
A SHORT COMMUNICATION ON COLON SPECIFIC DRUG DELIVERY SYSTEMS
Authors :
Fariha Ali, B. Chandrasekhar Rao, Sushma Desai*
Abstract :
Colon specific targeted drug delivery systems are developed and designed for the delivery of drugs exclusively in colon. The drugs can be delivered irrespective of their varied physicochemical characteristics like hydrophilic, hydrophobic, acidic or basic can be effectively used for treatment of chronic conditions advantageous over controlled and sustained release action for conditions like colon infections, irritable bowel syndrome etc. This mini review highlights the favorable colon anatomical and physiological conditions as a target site for many drugs having formulation challenges like solubility, stability, degradation and longer half-life and shorter transit time due to chronic conditions faced by patients led to the development of colon specific drug delivery systems. This paper briefly discusses about colon specific drug delivery system mechanisms like pH, microbial enzymes, timed release along with their suitable polymers and methodologies for development.
Keywords: Colon, Polymers, stability, chronic conditions.
Cite This Article:
Please cite this article in press Sushma Desai et al., A Short Communication On Colon Specific Drug Delivery Systems., Indo Am. J. P. Sci, 2026; 13(04).
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