Volume : 13, Issue : 04, April – 2026
Title:
RISK FACTORS ASSOCIATED WITH AMPUTATION IN PATIENTS WITH DIABETIC FOOT ULCER: A PROSPECTIVE OBSERVATIONAL STUDY
Authors :
Sadasiva Rao Galaba, Surya Narayana Polamuri, Hyma Tangirala, Sushma Dubbala, Pravallika Ravela
Abstract :
Background: Diabetic foot ulcer (DFU) is one of the most serious complications of diabetes mellitus and is a leading cause of non-traumatic lower limb amputations worldwide. Several demographic, lifestyle, clinical, and metabolic factors contribute to the progression of DFU and increase the risk of amputation. Early identification of these factors is essential to improve patient outcomes and reduce the burden of limb loss.
Methods: A hospital-based observational study was conducted among 80 patients diagnosed with diabetic foot ulcers. Data were collected using a structured data collection form including demographic characteristics, lifestyle factors, comorbid conditions, clinical parameters, ulcer severity, treatment adherence, and laboratory values. Statistical analysis was performed using descriptive statistics, chi-square tests, and multiple regression analysis.
Results: Among the 80 patients, 53 (66.25%) underwent amputation. Higher amputation rates were observed among patients with peripheral arterial disease (79.1%), obesity (93.3%), long-term diabetes (73.5%), severe neuropathy (69.4%), and higher Wagner grades (87.5%). Poor medication adherence and poor foot-care practices were also associated with increased amputation risk.
Conclusion: The findings suggest that DFU-related amputation is influenced by multiple clinical and behavioral factors. Early diagnosis, proper glycemic control, improved foot care practices, and multidisciplinary management are essential to reduce amputation risk among diabetic patients.
Keywords: Diabetic Foot Ulcer (DFU), Amputation, Diabetes Mellitus, Peripheral Arterial Disease, Peripheral Neuropathy, Wagner Classification, Glycemic Control, Risk Factors, Foot Care Practices, Medication Adherence
Cite This Article:
Please cite this article in press Sadasiva Rao Galaba et al., Risk Factors Associated With Amputation In Patients With Diabetic Foot Ulcer: A Prospective Observational Study., Indo Am. J. P. Sci, 2026; 13(04).
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