Volume : 13, Issue : 04, April – 2026
Title:
DESIGN AND IN-VITRO EVALUATION OF PENTAZOCINE HYDROCHLORIDE MICROEMULSION TRANSDERMAL GELS
Authors :
Y. Sarah Sujitha *, Chinthamakula Vishnu Sai
Abstract :
The purpose of this study was to design and in-vitro evaluation of Pentazocine hydrochloride microemulsion transdermal gels.. Results: The mean particle size of the microemulsion gel formulation was found to be 126.6 ± 0.1 nm and The PDI was found to be in the range of 0.341 ± 0.6.. The mean zeta potential value of the microemulsion gel was found to be -26.1 ± 0.3 mV. Transmission electron micro-graphs of the optimized formulation, revealed that the globules of the developed microemulsions are spherical and discrete and have uniform droplet size distribution. The in vitro permeation was found to be 92.2 ± 0.5% and 76.4 ±0.1% in 24 hours for microemulsion gel and plain gel respectively
Key words Microemulsion, particle size & Transmission electron micro-graphs.
Cite This Article:
Please cite this article in press Y. Sarah Sujitha et al., Design And In-Vitro Evaluation Of Pentazocine Hydrochloride Microemulsion Transdermal Gels., Indo Am. J. P. Sci, 2026; 13(04).
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