Volume : 13, Issue : 01, January – 2026

Title:

GUGGULSTERONE E AND Z QUANTITATIVE ESTIMATION IN POLYHERBAL TABLET FORMULATION BY HPLC

Authors :

Prof. Dr. Pankaj M Chaudhari, Miss. Kalyani A. Chaudhari, Miss. Puja S. Gaikwad, Miss. Payal V. Nikumbhe, Miss. Tashvita P. Magare,

Abstract :

Guggulsterone is the active constituent of Commiphora mukul which is the main ingredients of formulation. The formulation was found to be potent for Triton X-100 induced Hyperlipidemic model of anti-hyperlipidemic activity. In the present study an attempt has been made to develop a HPLC method for quantitative estimation of Guggulsterone in anti-hyperlipidemic polyherbal tablet formulation. The HPLC separation was performed on a C18 column (250 x 4.6 mm, 5 µ) using solvent system acetonitrile: water (45: 55) at flow rate of 2 ml/min. Detection was carried out at 242 nm. The content of guggulsterone E & Z in polyherbal formulation was found to be 0.561 mg/tablet.
KEYWORDS: Guggulsterone, Commiphora mukul, HPLC, polyherbal formulation, anti-hyperlipidemic.

Cite This Article:

Please cite this article in press Pankaj M Chaudhari et al., Guggulsterone E And Z Quantitative Estimation In Polyherbal Tablet Formulation By Hplc, Indo Am. J. P. Sci, 2026; 13(01).

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