Volume : 13, Issue : 06, June – 2026
Title:
A META ANALYSIS STUDY ON NON -ALCOHOLIC FATTY LIVER DISEASE IN CHILDRENS
Authors :
Rangam Chariitha*, K. Preethi, Reddigari Kalpana, Ramsha Khanam,T.Mangilal
Abstract :
Non-Alcoholic Fatty Liver Disease (NAFLD) is an increasingly prevalent condition among children and adolescents, often associated with multiple metabolic comorbidities. This systematic review analysed data from 20 published studies, comprising a total of 9,946 patients, to evaluate age-wise distribution, gender differences, associated comorbidities, and treatment patterns in NAFLD. The age-wise distribution revealed that NAFLD was most common in the 2–5 years age group and higher prevalence among males. Among the identified causes, obesity was the most prominent factor. Other comorbidities observed were obesity, dyslipidaemia and insulin resistance, followed by elevated alanine aminotransferase (ALT) levels, type 2 diabetes mellitus, hypertension, metabolic syndrome, and hyperuricemia. In conclusion, NAFLD in children is strongly associated with early age onset, male predominance, and multiple metabolic comorbidities, particularly obesity and insulin resistance. Early diagnosis and comprehensive management strategies are essential to prevent disease progression and associated complications.
Keywords: Non-Alcoholic Fatty Liver Disease, Paediatric NAFLD, Children and adolescents, Obesity, Dyslipidaemia, Type 2 Diabetes Mellitus, Hypertension, Alanine aminotransferase (ALT), Fat accumulation in liver, Lifestyle modification, Pioglitazone, Vitamin E, Metformin, Statins.
Cite This Article:
lease cite this article in press Rangam Chariitha et al., A Meta Analysis Study On Non -Alcoholic Fatty Liver Disease In Childrens.., Indo Am. J. P. Sci, 2026; 13(06).
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