Volume : 13, Issue : 03, March – 2026

Title:

FORMULATION AND EVALUATION OF A TOPICAL ANTI-AGING GEL CONTAINING SWEET POTATO -DERIVED HYALURONIC ACID-LIKE POLYSACCHARIDES

Authors :

Shaista Fathima, Reddygari Srujana, Sameera Begum, Rathod Manjula, Reddycherla saipriya, Dr.Sunitha.D*

Abstract :

Background: Skin aging is a complex process linked to reduced skin hydration, loss of elasticity, and increased oxidative stress. Hyaluronic acid (HA), a naturally occurring biopolymer, is essential for maintaining skin moisture and structural integrity. This makes it a key ingredient in anti-aging skin products.
Objectives: This study aimed to extract hyaluronic acid from plant-based sources and create a stable, safe, and effective herbal anti-aging gel formulation.
Materials And Procedures: We extracted hyaluronic acid from sweet potato, local potato, and lettuce leaf residues using acetic acid treatment followed by bath sonication. We characterized the extracted HA using Fourier-transform infrared spectroscopy (FTIR) and high-performance liquid chromatography (HPLC). We evaluated its antioxidant activity. Based on the results, we formulated an anti-aging gel with hyaluronic acid as the main active ingredient, along with natural antioxidants like butterfly pea flower extract, rose extract, and aloe vera. We assessed the gels for physicochemical properties, including pH, viscosity, spreadability, homogeneity, appearance, and stability.
Results: The hyaluronic acid extracted from sweet potato showed higher antioxidant activity compared to the other plant sources. The anti-aging gels we formulated had an acceptable pH for skin application, good spreadability, stable viscosity, a uniform appearance, and showed no signs of instability or skin irritation.
Key Words: Hyaluronic acid, anti-aging gel, antioxidant activity, herbal formulation, skin hydration.

Cite This Article:

Please cite this article in press Sunitha.D et al., Formulation And Evaluation Of A Topical Anti-Aging Gel Containing Sweet Potato -Derived Hyaluronic Acid-Like Polysaccharides., Indo Am. J. P. Sci, 2026; 13(03).

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