Volume : 13, Issue : 03, March – 2026

Title:

PHARMACOGNOSY IN THE ERA OF NANOTECHNOLOGY: HERBAL-BASED NANOFORMULATIONS AND THEIR THERAPEUTIC APPLICATIONS

Authors :

Karche Pranjali Vishwambhar*, Kashid Rohan Madhukar, Swapnali Yuvraj Kengar, Vagare Dnyaneshwari Balasaheb, Dr. Rahul Ishwara Jadhav

Abstract :

Oral drug delivery remains the most preferred route of administration due to its convenience and patient compliance. However, poor aqueous solubility is one of the major challenges limiting the bioavailability of many therapeutic agents. A significant proportion of newly developed drugs belong to Biopharmaceutical Classification System (BCS) Class II and IV, where solubility is the primary limiting factor. Various conventional and advanced strategies have been developed to overcome this issue, including particle size reduction, salt formation, solid dispersions, lipid-based systems, and nanotechnology-driven approaches. These techniques enhance dissolution rate, improve drug absorption, and increase therapeutic effectiveness. This review provides a comprehensive overview of mechanisms, techniques, advantages, and recent advancements in improving oral bioavailability of poorly soluble drugs.
Ke ywords: Oral bioavailability, BCS classification, Poor solubility, Nanotechnology, Drug delivery systems

Cite This Article:

Please cite this article in press Rahul Ishwara Jadhav et al., Emerging Strategies To Enhance Oral Bioavailability Of Poorly Water-Soluble Drugs: From Bcs Classification To Advanced Delivery Systems., Indo Am. J. P. Sci, 2026; 13(03).

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