Volume : 13, Issue : 05, May – 2026
Title:
HERBAL-PROBIOTIC BASED NOVEL FORMULATION FOR GUT MICROBIOTA MODULATION IN IBS AND IBD
Authors :
Dr. R. H. Kale, Dr. R. R. Pagore, Dr. A. D. Gattani, Prof. S. N. Gadekar
Abstract :
The present study was carried out to develop and evaluate a herbal-probiotic syrup formulation for gut microbiota modulation in IBS and IBD. Medicinal herbs including Aloe vera, Curcuma longa, Mentha piperita, Zingiber officinale, and Glycyrrhiza glabra were selected for formulation development due to their anti-inflammatory and gastroprotective properties. Hydroalcoholic extracts of the herbs were combined with probiotic strains Lactobacillus acidophilus and Bifidobacterium bifidum to prepare five syrup formulations. The prepared formulations were evaluated for physicochemical properties, probiotic viability, antioxidant activity, anti-inflammatory activity, and stability. Among all formulations, F3 showed better stability, probiotic survival, and biological activity. The study suggests that herbal-probiotic syrup may serve as a promising natural therapeutic approach for gut microbiota restoration and management of IBS and IBD.
Keywords: Herbal-Probiotic Syrup, Gut Microbiota, IBS, IBD, Probiotics, Antioxidant Activity, Anti-inflammatory Activity, Gastrointestinal Disorders, Polyherbal Formulation, Synbiotic Therapy
Cite This Article:
Please cite this article in press R. H. Kale et al., Herbal-Probiotic Based Novel Formulation For Gut Microbiota Modulation In Ibs And Ibd., Indo Am. J. P. Sci, 2026; 13(05).
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