Volume : 13, Issue : 09, September – 2026
Title:
CUBOSOMAL HYDROGEL-BASED DRUG DELIVERY SYSTEMS FOR DIABETIC WOUND HEALING: A COMPREHENSIVE REVIEW
Authors :
Dr. A. Seetha Devi*, Ramya sri. T, Bhargavi. G, Dr. A. Seetha Devi
Abstract :
Wound healing in diabetes is a serious problem due to slow wound closure, inflammation, and vulnerability to infections. Standard methods of topical treatment suffer from inadequate penetration and inability to provide continuous release of drugs. Mupirocin is a commonly used topical antibiotic that shows efficacy against Gram-positive bacteria but has limited performance due to low adherence and brief time of stay on the wound. The recent advancements in the field of nanotechnology have provided Cubosomes as novel carriers of drugs because of the unique characteristics such as bicontinuous cubic structure, high load, and controlled release.
This paper provides information about the benefits of using mupirocin-loaded cubosomal hydrogels (cubogels) for diabetic wound healing. Information concerning the mechanism of diabetic wounds and limitations of standard therapies is provided. Also, the advantages of cubosomes and hydrogel carriers are presented. Furthermore, recent developments in the field of nanocarrier-based treatments of wounds are discussed in order to identify the gaps in the current state of knowledge. Despite the fact that many efforts were put into creating innovative formulations, there are not enough studies devoted to the use of cubosomal hydrogels for mupirocin treatment of diabetic wounds.
Keywords: Cubosomes, Cubosomal Hydrogel, Diabetic Wound Healing, Topical Drug Delivery, Advanced Drug Delivery Systems
Cite This Article:
Please cite this article in press A. Seetha Devi et al., Cubosomal Hydrogel-Based Drug Delivery Systems For Diabetic Wound Healing: A Comprehensive Review.,. Indo Am. J. P. Sci, 2026; 13(09).
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